개방성 균음전 결핵공통의 임상 및 세균, 병리학적 고찰

Abstract

After sufficient antituberculosis chemotherapy some cases end up open-negative cavity status. Many reported the healing of the lesion, but it is very rare. Fifteen patients of open-negative status were reviewed clinically and resected lung tissues were examined both bacteriologically and pathologically. The results were as follows: 1. Bacteriological studies on the pre-operative sputum were negative for suficient intervals in all cases. 2. Thirteen patients were male and 2 patients were female. 3. Ten of the patients were between the ages of 26 and 35 years. 4. Average duration of illness was 48.4 months. 5. Five patients were originally treated and 10 were the cases of rctrcatmcnt, 6. Average number of the cavity was 2.1 and the average size of the cavity was 3.4cm. The average thickness of the cavity wall was 3.2mm. and there were fibrous infitration around the cavities in two thirds of the specimens (66.796) 7. Direct smear of the cavity content and cavity wall revealed acid fast bacilli positive in twelve patients (80%) and positive culture for tubercle bacilli in two cases (I3.396). 8. The resected lung tissues were examined pathologically. They revealed no case of healed cavity and eleven of them revealed moderate to mild caseation necrosis of the wall with moderate inflammatory reaction. Two of them revealed active tuberculous inflammation. 9. The result was discussed with the references. 10. All the patients operated on were well after surgery and no complication had developed.