심장, 폐기능 연구에서의 의용 계통 해석학의 이용

Abstract

Mathematical and Engineering approaches have been applied for the analysis and quantification of biomedical research. In this paper, the following biomedical system analysis methods are applied to evaluate tbe cardiac pulmonary functions: I. Cardiac Pumping function study; (1-a) Sensitivity and after-load independence of zero-load aortic flow, (I-b) Relation between computed zero-load aortic flow and cardiac muscle mechanics. 2. Study of Ventricular output flow and power; (2-a) Non-invasive cardiac output estimation based upon a mathematical model of the aorta, (2-b) Significance of left ventricular pressure waveform on changes in stroke volume during pulsatile left ventricular bypass, (2-c) Performance criteria for optimization of cardiac assistance. 3. Dynamic changes of cerebral blood flow and oxygen stores to hypoxia, (3-a) Frequency-domain Analysis of oxygen stores during hypoxia in goats, (3-b) Dynamic characteristics of cerebral blood flow response to sinusoidal hypoxia. The above seven examples of cardio-pulomonary research demonstrate the usefulness of the biomedical system analysis for the evaluation of transient phenomena and dynamic characteristics of the physiological systems.