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Mesenchymal stem cell-mediated functional tooth regeneration in swine
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Seo, Byoung-Moo | - |
dc.contributor.author | Sonoyama, Wataru | - |
dc.contributor.author | Liu, Yi | - |
dc.contributor.author | Fang, Dianji | - |
dc.contributor.author | Yamaza, Takayoshi | - |
dc.contributor.author | Zhang, Chunmei | - |
dc.contributor.author | Liu, He | - |
dc.contributor.author | Gronthos, Stan | - |
dc.contributor.author | Wang, Cun-Yu | - |
dc.contributor.author | Shi, Songtao | - |
dc.contributor.author | Wang, Songlin | - |
dc.date.accessioned | 2010-05-17T23:34:58Z | - |
dc.date.available | 2010-05-17T23:34:58Z | - |
dc.date.issued | 2006-12 | - |
dc.identifier.citation | Plos One 1(1): e79 | en |
dc.identifier.issn | 1932-6203 | - |
dc.identifier.uri | https://hdl.handle.net/10371/66628 | - |
dc.description.abstract | Mesenchymal stem cell-mediated tissue regeneration is a promising approach for regenerative medicine for a wide range of applications. Here we report a new population of stem cells isolated from the root apical papilla of human teeth (SCAP, stem cells from apical papilla). Using a minipig model, we transplanted both human SCAP and periodontal ligament stem cells (PDLSCs) to generate a root/periodontal complex capable of supporting a porcelain crown, resulting in normal tooth function. This work integrates a stem cell-mediated tissue regeneration strategy, engineered materials for structure, and current dental crown technologies. This hybridized tissue engineering approach led to recovery of tooth strength and appearance | en |
dc.language.iso | en | en |
dc.publisher | Public Library of Science | en |
dc.title | Mesenchymal stem cell-mediated functional tooth regeneration in swine | en |
dc.type | Article | en |
dc.contributor.AlternativeAuthor | 서병무 | - |
dc.identifier.doi | 10.1371/journal.pone.0000079 | - |
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