방광암

Abstract

Carcinoma of the bladder appears to be the most common tumor of the genito-urinary system, but incidence of this tumor per population is not yet determined in Korea. The etiology of the bladder tumor is not known, in spite of better knowledges about more specific carcinogens. The treatment of choice has been surgery. The radiation therapy, chemotherapy and/or immunotherapy as an alternative or adjunctive measure to sur gery has recently been tried but the result is not yet satisfactory. The grading and staging of the tumor arc imperative to evaluate the result of treatment and prognosis, A multidisciplinary approach offers better result in diagnosis and treatment. Tbe author carried out an epidemiological study and reviewed reports of experiences in bladder tumors from tbe Department of Urology, Seoul National University Hospital during last 20 years. We developed a histotopographic technic for analysis of urothelial lesions adjacent to carcinoma of urinary bladder, This technic provides valuable information for proper surgical procedure in regard to p itient's prognostic factors and for oncogenic relationship with von Brunn's nest, cystitis cystica , polypoid cystitis, dysplasia and in situ carcinoma. A study of 13 total cystectomy specimens using this technic revealed CIS zone' measuring O. 5 to 2. Oem in diameter from the overt carcinoma in all cases. The distribution of CIS was very irregular and CIS was also noted even in the cases of well differentiated papillary carcinoma.