S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 24 No.1 (1983)
여성 배난 주기중 뇨 Estrone-3a-glucuronide와 Pregnanediol-3a-glucuronide의 농도변화
Changes of Urinary Estrone-3a- and Pregnanediol-3a-glucuronide Levels during Human Ovarian Cycles.
- 한정호; 채범석
- Issue Date
- 서울대학교 의과대학
- Seoul J Med, Vol.24 No.1, pp. 53-65
- To assess the reliability of monitoring overian function
and fertile period, the concentrations of urinary LH, estrone-3a-glucuronide CE,-G) and pregnanediol3a-
glucuronideCP'diol-G) were measured by direct
radioimmunoassay on unextracted daily samples of
early morning urine throughout the 6 consecutive
ovarian cycles of 14 Korean women.
The changes in levels of urinary E,-G, P'diol-G
and E,-G/P'diol-G ratio during ovarian cycle, the
intra-individual variations, and the suitability of various
mathematical indices for predicting the start
and finishing of the fertile period were observed.
The results have shown that the measurement of
E,-G and P'diol-G in early morning urine may be
of value for monitoring follicular development and
luteal function in women over long periods of time
without the problems of stress and inconvenience to
the patients. The most feasible indices for predicting
the start and finishing of the fertile period were
obtained in urinary E,-G and E,-G/P'diol-G ratio
This study was supported by World Health Organization.