S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 32 No.1 (1991)
Correlation between Pulse Oximetry Oxygen Saturation (SpO2) and Measured Arterial Oxygen Saturation (SaO2) and Arterial Oxygen Tension (PaO2) in Neonates
신생아에서 Pulse Oximetry에 의한 산소포화도(SpO2)와 동맥혈 산소포화도(SaO2) 및 동맥혈 산소분압(PaO2)의 상관관계
- Choi, Jung-Hwan; Park, Won Soon; Yun, Chong Ku
- Issue Date
- Seoul J Med, Vol.32 No.1, pp. 17-25
- Pulse oximetry has recently been introduced as a method for continuous
and non-invasive transcutaneous monitoring of arterial oxygen saturation in neonates.
The purpose of our study was to determine the reliability, accuracy, and practicability
of pulse oximetry for monitoring arterial oxygenation in sick newborn infants. Pulse
oximetry oxygen saturation values (SpO2) were compared with simultaneously measured
arterial oxygen saturation values (Sa02) by a co-oximeter. The linear regression equation
for 65 data pairs was Y=24.53 + 0.726X (r=0.90, p <0.01). The difference between
measured Sa02 and pulse oximetry oxygen saturation (Sp02) was 0.44% ± 2.97%
(mean ± S.D.). The linear regression equation comparing measured Sa02 minus pulse
oximetry saturation (Sp02) was Y=-23.09 + 0.258X (r=0.58, p <0.01). This demonstrated
an increasing error of pulse oximetry with decreasing Sa02. Pulse oximetry oxygen
saturation (Sp02) also correlated well with measured arterial oxygen tension (Pa02),
and the upper reach of the S-shaped hemoglobin-oxygen dissociation curve was clear.
With a hypothetical alarm limit set at 92%, all hyperoxemic values (29/29) were correctly
identified (sensitivity 100%). Of the 78 paired values, 33 were classified correctly
as nonhyperoxemic (specificity 42%), and a total of 62 (29 + 33) out of the 107 paired
values were ranged correctly (accuracy 58%). The accuracy increased significantly with
an increase in alarm limit up to 94%, and it remained stable thereafter.
We conclude that pulse oximetry is a simple, accurate, noninvasive, and continuous
method of transcutaneously measuring arterial oxygen saturation, and hyperoxemia
can be detected by pulse oximetry with a high sensitivity provided that prior to use,
type-specific alarm limits are set.