Multiple Subcutaneous Nodules, Persistent High Fever and Lymphadenopathy Case - SNUCH CPC-33 -

Abstract

This 15-year-old boy was admitted for the second time to Seoul National University Children's Hospital (SNUCH) on February 28, 1988, because of intermittent high fever and lymph node swelling. His illness started in 1985 as repeated sore throat and high fever, for which he was brought to Korea University Hospital. There he underwent an oropharyngeal biopsy that was read as acute necrotizing inflammation. In August 1987, neck lymph node swelling and splenomegaly were noted in addition to the intermittent fever. On February 29, 1988, he was admitted to SNUCH to receive a lymph node biopsy, which revealed necrotizing and granulomatous inflammation with heavy eosinophi-lia. He was born via normal full term spontaneous delivery, and his immediate postnatal course was uneventful. Although no specific disease could be recalled by the parents,intermittent high fever, otitis, and sore throat were recurrent symptoms and si-gns through his infancy and early childhood.