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Large artery intracranial occlusive disease: a large worldwide burden but a relatively neglected frontier

Cited 354 time in Web of Science Cited 383 time in Scopus
Authors
Gorelick, Philip B; Wong, Ka Sing; Bae, Hee-Joon; Pandey, Dilip K
Issue Date
2008-06-07
Publisher
American Heart Association
Citation
Stroke. 2008;39(8):2396-2399
Keywords
Arterial Occlusive Diseases/*epidemiology/etiology/therapyCerebral ArteriesHumansRisk FactorsStroke/*epidemiology/etiology/therapy*World Health
Abstract
BACKGROUND AND PURPOSE: Large artery intracranial occlusive disease (LAICOD) is a common and important stroke subtype. In this commentary, we review key epidemiological aspects of LAICOD. SUMMARY OF REVIEW: LAICOD has emerged as the most common stroke subtype worldwide and is associated with a high risk of recurrent stroke. Hypotheses have been proposed to explain causation, which include such factors as traditional cardiovascular risk factors, high blood volume states, and genetic abnormalities. Approaches to treatment such as antithrombotic therapies, revascularization procedures, and counterpulsation devices hold promise. CONCLUSIONS: LAICOD poses a major stroke problem worldwide and is likely the most common stroke subtype. The etiology and treatment of this disorder remain poorly defined. International collaborations are needed to pool collective knowledge and develop definitive studies to better understand causation and treatment of LAICOD.
ISSN
1524-4628 (Electronic)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18535283

http://stroke.ahajournals.org/cgi/reprint/39/8/2396.pdf

https://hdl.handle.net/10371/67839
DOI
https://doi.org/10.1161/STROKEAHA.107.505776
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Neurology (신경과학교실)Journal Papers (저널논문_신경과학교실)
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