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Central skull base lymphoma in children: MR and CT features

Cited 18 time in Web of Science Cited 17 time in Scopus
Authors
Choi, Hei-Kyung; Cheon, Jung-Eun; Kim, In-One; Youn, Byung Jae; Jung, Ah Young; Shin, Su-Mi; Kim, Woo Sun; Yeon, Kyung Mo
Issue Date
2008-06-19
Publisher
Springer Verlag
Citation
Pediatr Radiol. 38(8):863-867
Keywords
ChildChild, PreschoolFemaleHumansLymphoma/*diagnosisMagnetic Resonance Imaging/*methodsMaleSkull Base Neoplasms/*diagnosisTomography, X-Ray Computed/*methods
Abstract
BACKGROUND: Central skull base tumours are rare in children. OBJECTIVE: To characterize the imaging features of central skull base lymphoma in children to aid its diagnosis. MATERIALS AND METHODS: The authors reviewed the CT findings (available in three patients) and MR findings (available in four patients) in four patients (three boys, one girl; age 2-12 years) with pathologically proven lymphoma (two with Burkitt lymphoma, two with B-cell lymphoma) involving the central skull base. Tumour location and extent, MRI signal intensities, noncontrast CT attenuation, patterns of enhancement, and changes in adjacent structures were evaluated. RESULTS: All four tumours involved the sphenoid bone. In three patients, the tumour extended to the ethmoid sinus and both cavernous sinuses. All lesions were isointense solid masses on T2-weighted images and showed avid enhancement, except for one lesion with a focal necrosis. All tumours were associated with adjacent dural thickening. Non-contrast CT showed highly attenuating masses and permeative bone destruction in the central skull base. CONCLUSION: Lymphoma involving the central skull base in children is visualized as an isointense mass on T2-weighted MRI with marked contrast enhancement and adjacent dural thickening, and as a highly attenuating mass on noncontrast CT with permeative or erosive bone destruction patterns.
ISSN
0301-0449 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18560821

http://www.springerlink.com/content/x82773545hq08855/fulltext.pdf

https://hdl.handle.net/10371/67845
DOI
https://doi.org/10.1007/s00247-008-0912-z
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College of Medicine/School of Medicine (의과대학/대학원)Radiology (영상의학전공)Journal Papers (저널논문_영상의학전공)
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