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The involvement of human amnion in histologic chorioamnionitis is an indicator that a fetal and an intra-amniotic inflammatory response is more likely and severe: clinical implications
Cited 79 time in
Web of Science
Cited 87 time in Scopus
- Authors
- Issue Date
- 2008-12-03
- Publisher
- Elsevier
- Citation
- Placenta. 2009;30(1):56-61
- Keywords
- Adult ; Amniocentesis ; Amnion/enzymology/*pathology ; Amniotic Fluid/chemistry/microbiology ; C-Reactive Protein/analysis ; Chorioamnionitis/*diagnosis/microbiology ; Chorion/*pathology ; Female ; Fetal Blood/chemistry ; Gestational Age ; Humans ; Infant, Newborn ; Infant, Newborn, Diseases/etiology/*pathology ; Male ; Matrix Metalloproteinase 8/analysis ; Predictive Value of Tests ; Pregnancy ; Premature Birth ; Sepsis/complications/*pathology ; Young Adult
- Abstract
- OBJECTIVE: Amnionitis (inflammation of the amnion) is the final stage of extra-placental chorioamniotic inflammation. We propose that patients with "amnionitis", rather than "chorionitis" have a more advanced form of intra-uterine inflammation/infection and, thus, would have a more intense fetal and intra-amniotic inflammatory response than those without "amnionitis". STUDY DESIGN: The relationship between the presence of amnionitis, and a fetal and an intra-amniotic inflammatory response was examined in 290 singleton preterm births (
- ISSN
- 0143-4004 (Print)
- Language
- English
- URI
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19046766
http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WPD-4V1D7PY-1-1&_cdi=6988&_user=168665&_orig=search&_coverDate=01%2F31%2F2009&_sk=999699998&view=c&wchp=dGLzVtb-zSkWA&md5=2e6b0d35ad34779097eee7a534a0a1db&ie=/sdarticle.pdf
https://hdl.handle.net/10371/68034
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