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The involvement of human amnion in histologic chorioamnionitis is an indicator that a fetal and an intra-amniotic inflammatory response is more likely and severe: clinical implications

Cited 73 time in Web of Science Cited 79 time in Scopus
Authors
Park, Chan-Wook; Moon, Kyung Chul; Park, Joong Shin; Jun, Jong Kwan; Romero, Roberto; Yoon, Bo Hyun
Issue Date
2008-12-03
Publisher
Elsevier
Citation
Placenta. 2009;30(1):56-61
Keywords
AdultAmniocentesisAmnion/enzymology/*pathologyAmniotic Fluid/chemistry/microbiologyC-Reactive Protein/analysisChorioamnionitis/*diagnosis/microbiologyChorion/*pathologyFemaleFetal Blood/chemistryGestational AgeHumansInfant, NewbornInfant, Newborn, Diseases/etiology/*pathologyMaleMatrix Metalloproteinase 8/analysisPredictive Value of TestsPregnancyPremature BirthSepsis/complications/*pathologyYoung Adult
Abstract
OBJECTIVE: Amnionitis (inflammation of the amnion) is the final stage of extra-placental chorioamniotic inflammation. We propose that patients with "amnionitis", rather than "chorionitis" have a more advanced form of intra-uterine inflammation/infection and, thus, would have a more intense fetal and intra-amniotic inflammatory response than those without "amnionitis". STUDY DESIGN: The relationship between the presence of amnionitis, and a fetal and an intra-amniotic inflammatory response was examined in 290 singleton preterm births (
ISSN
0143-4004 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=19046766

http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6WPD-4V1D7PY-1-1&_cdi=6988&_user=168665&_orig=search&_coverDate=01%2F31%2F2009&_sk=999699998&view=c&wchp=dGLzVtb-zSkWA&md5=2e6b0d35ad34779097eee7a534a0a1db&ie=/sdarticle.pdf

https://hdl.handle.net/10371/68034
DOI
https://doi.org/10.1016/j.placenta.2008.09.017
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College of Medicine/School of Medicine (의과대학/대학원)Pathology (병리학전공)Journal Papers (저널논문_병리학전공)
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