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Pleomorphic xanthoastrocytoma associated with long-standing Taylor-type IIB-focal cortical dysplasia in an adult

Cited 5 time in Web of Science Cited 5 time in Scopus
Authors
Kim, Bomi; Chung, Chun-Kee; Myung, Jae Kyung; Park, Sung-Hye
Issue Date
2008-07-29
Publisher
Elsevier
Citation
Pathol Res Pract. 205 (2009) 113-117
Keywords
Astrocytoma/*complications/*pathologyBrain Neoplasms/*complications/*pathologyEpilepsy, Temporal Lobe/*complicationsHumansMagnetic Resonance ImagingMaleMalformations of Cortical Development/*complicationsMiddle Aged
Abstract
Brain tumor in combination with cortical dysplasia is one of the causes of epilepsy, but coexistence of these two entities is a rare event. We report a case of pleomorphic xanthoastrocytoma (PXA) arising in combination with Taylor-type IIB-focal cortical dysplasia. A 54-year-old male had been suffering from temporal lobe epilepsy for 40 years. Nine years ago (at the age of 45), a brain CT revealed a mass (1cm) in the uncal area, but the patient did not give consent to an operation. Later, he was admitted as an emergency case because of severe headache, and the tumor was removed. The tumor was diagnosed as PXA with anaplastic feature (mitotic count: 5/10HPF), and the brain around the tumor showed dysmorphic neurons and balloon cells. Therefore, the tumor was assumed to be associated with the brain, with Taylor-type-IIB focal cortical dysplasia. The patient's condition deteriorated, with tumor recurrence and widespread leptomeningeal seeding to the whole spinal cord. He died 17 months after tumor removal.
ISSN
0344-0338 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18657915

http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B7GW5-4T2S00X-1-7&_cdi=20449&_user=168665&_orig=search&_coverDate=02%2F15%2F2009&_sk=997949997&view=c&wchp=dGLbVzW-zSkWA&md5=8d3db2d664134869d1ec8ca9c6471920&ie=/sdarticle.pdf

https://hdl.handle.net/10371/68040
DOI
https://doi.org/10.1016/j.prp.2008.04.017
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College of Medicine/School of Medicine (의과대학/대학원)Pathology (병리학전공)Journal Papers (저널논문_병리학전공)
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