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Association between endometriosis and polymorphisms in endostatin and vascular endothelial growth factor and their serum levels in Korean women

Cited 29 time in Web of Science Cited 27 time in Scopus
Authors

Kim, Jung Gu; Kim, Ja Yeon; Jee, Byung Chul; Suh, Chang Suk; Kim, Seok Hyun; Choi, Young Min

Issue Date
2007-05-08
Publisher
Elsevier
Citation
Fertil Steril. 2008;89(1):243-245
Keywords
AdultAsian Continental Ancestry Group/*geneticsCase-Control StudiesEndometriosis/*blood/*geneticsEndostatins/*blood/*geneticsFemaleGene FrequencyGenetic Predisposition to DiseaseHumansKoreaRisk AssessmentRisk FactorsSeverity of Illness IndexVascular Endothelial Growth Factor A/*blood/*geneticsPolymorphism, Single Nucleotide
Abstract
The aim of present study was to evaluate the relationship between endometriosis and polymorphisms in the endostatin and vascular endothelial growth factor (VEGF) genes, and their levels in serum in a Korean population. Serum endostatin levels (but not VEGF levels) were negatively correlated with the development of endometriosis, specifically in early-stage endometriosis patients, compared with women without endometriosis, but endometriosis was not associated with the endostatin G(4349)A and VEGF C(936)T polymorphisms.
ISSN
1556-5653 (Electronic)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=17482599

http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6T6K-4NNPH89-J-1&_cdi=5033&_user=168665&_orig=search&_coverDate=01%2F31%2F2008&_sk=999109998&view=c&wchp=dGLbVtb-zSkWA&md5=e03e250ae8ed907f7fc19c78d8b43ba2&ie=/sdarticle.pdf

https://hdl.handle.net/10371/68049
DOI
https://doi.org/10.1016/j.fertnstert.2007.02.023
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