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Retrospective multicenter study of a clinicopathologic analysis of pseudomyxoma peritonei associated with ovarian tumors (KGOG 3005)

Cited 11 time in Web of Science Cited 14 time in Scopus
Authors
Lee, J K; Song, S H; Kim, I; Lee, K H; Kim, B G; Kim, J W; Kim, Y T; Park, S Y; Cha, M S; Kang, S B
Issue Date
2008-02-06
Publisher
Wiley-Blackwell
Citation
Int J Gynecol Cancer. 2008;18(5):916-920
Keywords
AdolescentAdultAgedAged, 80 and overFemaleHumansMiddle AgedOvarian Neoplasms/*complications/*pathology/surgery/therapyPrognosisPseudomyxoma Peritonei/*complications/*pathology/surgery/therapyRetrospective StudiesSurvival Rate
Abstract
The purpose of this study is to assess clinicopathologic features of pseudomyxoma peritonei (PMP) that has ovarian pathology and its relationship with the prognosis. From 1995 to 2004, the clinical records and follow-up data of 35 patients with PMP, which had primarily originated from the ovary, were collected from 11 institutes of gynecologic oncology in Korea and retrospectively analyzed. All patients had ovarian lesion histologically confirmed with PMP. The mean age at diagnosis was 53.7 years (range: 16-82 years). There were 25 (71.4%) patients with disseminated peritoneal adenomucinosis, 5 (14.3%) with peritoneal mucinous carcinomatosis with intermediate group, and 5 (14.3%) with peritoneal mucinous carcinomatosis. The clinical stages at diagnosis were IA in 2 patients, IIIB in 4, IIIC in 23, IV in 1, and unknown in 5. In preoperative tumor markers, the positive rates were 72% (CA125), 47.4% (CA19-9), and 84.6% (CEA). Thirty-four patients underwent surgical staging or cytoreduction, and then 27 patients (77%) received adjuvant chemotherapy that was given to patients in a nonuniform fashion. The 5-year survival for 35 patients was 87%. Survival rate was significantly lower in patients >50 years of age (P = 0.002). Our data showed that age of the patient is the only significant prognostic factor in PMP that has ovarian lesion.
ISSN
1525-1438 (Electronic)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18248391

http://hdl.handle.net/10371/68077
DOI
https://doi.org/10.1111/j.1525-1438.2007.01146.x
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College of Medicine/School of Medicine (의과대학/대학원)Obstetrics & Gynecology (산부인과전공)Journal Papers (저널논문_산부인과학전공)
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