에타놀을 이용한 신 동맥 색전법에 관한 실험적 연구

Abstract

Artificial renal artery embolization was induced using ethanol in rabbits to determine the adequate concentration and amount of the ethanol to induce total renal ablation. A series of selective renal arteriography was done immediately, 1 week and 4 weeks after infusion of ethanol. The results were as follows: 1. There was no visible obstruction of renal artery after infusion of 60% ethanol 0.2ml/kg. 2. Incomplete obstruction of renal artery was produced in majority, after infusion of 80% ethanol 0.2ml/kg. 3. Incomplete obstruction of renal artery was produced in all cases after infusion of 8096 ethanol 0.5ml/kg. 4. Incomplete obstruction of renal artery was produced in majority, after infusion of absolute ethanol 0.2ml/kg, and it became complete obstruction above half cases after 4 weeks. 5. Complete obstruction of renal artery was produced after infusion of absolute ethanol O.5ml/kg, in majority initially and in all cases later on. It was considered that ethanol is an effective agent for complete renal arterial ocelusion and O. 2 to O. 5ml/kg of absolute ethanol is effective minimal dose for complete renal arterial occlusion.