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Clinical outcomes and patency of self-expanding metal stents in patients with malignant colorectal obstruction: a prospective single center study

Cited 52 time in Web of Science Cited 52 time in Scopus
Authors
Im, Jong Pil; Kim, Sang Gyun; Kang, Hyoun Woo; Kim, Joo Sung; Jung, Hyun Chae; Song, In Sung
Issue Date
2008-04-30
Publisher
Springer Verlag
Citation
Int J Colorectal Dis. 23(8):789-794
Keywords
AdultAgedAged, 80 and overColorectal Neoplasms/*complicationsEndoscopy, GastrointestinalFemaleForeign-Body MigrationHumansIntestinal Obstruction/etiology/*surgeryMaleMiddle AgedPalliative CareProspective StudiesRecurrence*StentsStomach Neoplasms/*complicationsTreatment OutcomeYoung Adult
Abstract
BACKGROUNDS AND AIMS: Self-expanding metal stents (SEMS) have been used as a palliative treatment for malignant colorectal obstruction. However, the reports about primary stent patency rate and associated factors have been limited. This study was performed to evaluate clinical outcomes and factors associated with long-term complications and patency of SEMS in patients with malignant colorectal obstruction. MATERIALS AND METHODS: Patients who underwent palliative endoscopic placement with uncovered SEMS for a malignant colorectal obstruction were prospectively enrolled at Seoul National University Hospital between April 2005 and August 2007. RESULTS: Forty-nine patients underwent 51 SEMS placements. Obstruction sites were rectum in 15 patients (30.6%), descending or sigmoid colon in 25 (51.0%), and transverse colon in nine (18.4%), respectively. The causes of obstruction were colorectal cancer in 36 patients (73.5%), direct invasion of gastric cancer in seven (14.3%) and others in six (12.2%). Technical success was achieved in 100% and clinical success in 86%, and there was one procedure-related perforation. Re-obstruction and migration occurred in 16% and 6%, respectively, during mean follow-up period of 331 days. Median stent patency duration was 204 days, and patency rates at 30, 90, and 180 days were 91.2%, 81.0%, and 53.3%, respectively, which was not associated with patient demographics, site of obstruction, or palliative chemotherapy. CONCLUSION: Endoscopic SEMS placement is a safe and effective palliative treatment for malignant colorectal obstruction, and overall long-term complication and patency were favorable irrespective of the palliative chemotherapy.
ISSN
0179-1958 (Print)
Language
English
URI
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=18443807

http://www.springerlink.com/content/l5k2650n0g745245/fulltext.pdf

http://hdl.handle.net/10371/68212
DOI
https://doi.org/10.1007/s00384-008-0477-1
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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