S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 36 No.1 (1995)
Cryptosporidiosis in a Leukemia Child with Severe Diarrhea
- Issue Date
- Seoul J Med, Vol.36 No.1, pp. 29-34
- Protozoa of the genus Cryptoporidium are smallc occidian parasites
that infect the mucosal epithelium of a variety of animals and humans, causing
protracted diarrhea in immunodeficient or malnourished patients as well as selflimited
illness in previously healthy individuals.
Cryptosporidiosis in a resected appendix from a child with acute lymphoblastic
leukemia is reported. He had had severe protracted watery diarrhea with abdominal
pain for one month. The standard hematoxylin and eosin stain revealed many
spherical, basophilic organisms on the apical surface of the mucosal epithelial cells.
The various stages of the Cryptosporidium paroum were identified by electron
It is important to recognize this organism because it is a widespread pathogen of
diarrheal illness and may cause life-threatening disease in immunocompromised
patients especially in acquired immune deficiency syndrome patients.