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Ceramic bioactivity: progresses,challenges and perspectives

Cited 63 time in Web of Science Cited 68 time in Scopus
Authors

Lee, K-Y; Park, M; Kim, H-M; Lim, Y-J; Chun, H-J; Kim, H; Moon, S-H

Issue Date
2006-05
Publisher
IOP Publishing
Citation
Biomed. Mater. 1, R31
Abstract
Bioactivity is a property of the ceramic surface which induces biological integration of living
soft and hard tissues. The core mechanism of bioactivity is surface biomineralization of
calcium phosphate nanocrystallites on ceramics with specific compositions and structures,
inspiring acellular and cellular strategies for bio-interactive materials with new physical,
chemical and biological functions. These include bioactive surface functionalizations on
metallic, ceramic and polymeric substrata for biomedical materials with different mechanical
properties, bioactive ceramic-polymer nanohybrids for soft tissue replacements and
engineering, template-textured depositions of biomimetic nano-calcium phosphate for
hybridization of bio-macromolecular and cellular functions, concerning which this paper
reviews with in vivo and in vitro fundamentals and perspectives in tissue engineering.
ISSN
1748-6041
Language
English
URI
https://hdl.handle.net/10371/68909
DOI
https://doi.org/10.1088/1748-6041/1/2/R01
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