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Reconstruction of human hard-palate mucosal epithelium on

Cited 22 time in Web of Science Cited 25 time in Scopus
Authors
Chung, Phil Hoon; Cho, Kwang Hyun; Ahn, Hi Tae; Park, Kyoung Chan; Chung, Jin Ho; Kim, Suk Wha; Sung, Myung Whun; Kim, Kwang Hyun; Eun, Hee Chul; Youn, Jai Il
Issue Date
2000-02
Publisher
Elsevier
Citation
Journal of Dermatological Science 2000;22:117-124
Keywords
Hard-palateDe-epidermized dermisThree-dimensional culture
Abstract
Artificial hard-palate mucosa equivalents were reconstructed using keratinocytes derived from normal human hard-palate and de-epidermized dermis. Reconstructed hard-palate mucosal epithelium formed in three-dimensional culture was compared to native hard-palate mucosal epithelium and reconstructed oral buccal mucosal epithelium with regard to keratin expression. Artificial hard-palate mucosal epithelium reconstructed in medium with delipidized serum showed a differentiation pattern similar to that of hard-palate epithelium in vivo. The present study also confirmed that keratinocytes derived from hard-palate mucosa are intrinsically different from those of nonkeratinizing oral surfaces.
ISSN
0923-1811
Language
English
URI
https://hdl.handle.net/10371/69624
DOI
https://doi.org/10.1016/S0923-1811(99)00056-0
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College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
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