S-Space College of Dentistry/School of Dentistry (치과대학/치의학대학원) Dept. of Dentistry (치의학과) Journal Papers (저널논문_치의학과)
Reconstruction of human hard-palate mucosal epithelium on
- Chung, Phil Hoon; Cho, Kwang Hyun; Ahn, Hi Tae; Park, Kyoung Chan; Chung, Jin Ho; Kim, Suk Wha; Sung, Myung Whun; Kim, Kwang Hyun; Eun, Hee Chul; Youn, Jai Il
- Issue Date
- Journal of Dermatological Science 2000;22:117-124
- Artificial hard-palate mucosa equivalents were reconstructed using keratinocytes derived from normal human hard-palate and de-epidermized dermis. Reconstructed hard-palate mucosal epithelium formed in three-dimensional culture was compared to native hard-palate mucosal epithelium and reconstructed oral buccal mucosal epithelium with regard to keratin expression. Artificial hard-palate mucosal epithelium reconstructed in medium with delipidized serum showed a differentiation pattern similar to that of hard-palate epithelium in vivo. The present study also confirmed that keratinocytes derived from hard-palate mucosa are intrinsically different from those of nonkeratinizing oral surfaces.
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