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Preferential expression of L-type amino acid transporter 1 in ameloblasts during rat tooth development

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Authors
Park, J.-C; Kim, Y.B; Yoon, J.H; Kim, H.-J; Kim, S.M; Kanai, Y; Endou, H; Kim, D.K
Issue Date
2004
Publisher
Wiley-Blackwell
Citation
Anat. Histol. Embryol. 33, 119-124
Abstract
Certain amino acid transport systems play an important role in supplying organic nutrients to each cell and for cell proliferation during tooth development. However, the mechanisms responsible for such actions are unclear. This study demonstrated for the first time that LAT1 and 4F2hc are expressed during tooth development in prenatal and postnatal rats, and that the transporters show cell-specific expression in ameloblasts, which are the epithelium-derived dental cells. LAT1 and 4F2hc expression was not observed in other dental cells of the developing teeth such as odontoblasts and cementoblasts. Overall, these results suggest that LAT1 and 4F2hc might play an important role in enamel formation. [ABSTRACT FROM AUTHOR]
Copyright of Anatomia, Histologia, Embryologia: Journal of Veterinary Medicine Series C is the property of Blackwell Publishing Limited and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
ISSN
0340-2096
Language
English
URI
https://hdl.handle.net/10371/69695
DOI
https://doi.org/10.1111/j.1439-0264.2003.00524.x
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College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
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