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Improved biological performance of Ti implants due to surface modification by micro-arc oxidation

Cited 513 time in Web of Science Cited 559 time in Scopus
Authors
Koak, Jai-Young; Li, Long-Hao; Kong, Young-Min; Kim, Hae-Won; Kim, Young-Woon; Kim, Hyoun-Ee; Heo, Seong-Joo
Issue Date
2004-06
Publisher
Elsevier
Citation
Biomaterials 2004;25:2867-2875
Keywords
titaniumoxidationbiocompatibilityin vitroosseointegrationin vivo
Abstract
The surface of a titanium (Ti) implant was modified by micro-arc oxidation (MAO) treatment. A porous layer was formed on the Ti surface after the oxidation treatment. The phase and morphology of the oxide layer were dependent on the voltage applied during the oxidation treatment. With increasing voltage, the roughness and thickness of the film increased and the TiO2 phase changed from anatase to rutile. During the MAO treatment, Ca and P ions were incorporated into the oxide layer. The in vitro cell responses of the specimen were also dependant on the oxidation conditions. With increasing voltage, the ALP activity increased, while the cell proliferation rate decreased. Preliminary in vivo tests of the MAO-treated specimens on rabbits showed a considerable improvement in their osseointegration capability as compared to the pure titanium implant.
ISSN
0142-9612
Language
English
URI
http://hdl.handle.net/10371/69802
DOI
https://doi.org/10.1016/j.biomaterials.2003.09.048
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College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
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