S-Space College of Medicine/School of Medicine (의과대학/대학원) Dept. of Medicine (의학과) The Seoul Journal of Medicine The Seoul Journal of Medicine Vol. 24 No.4 (1983)
Compartment Model을 이용한 정략적인 신장기능 해석에 관한 연구
A study on the Quantitative Evaluation of Renal Function using Compartment Model
- 유혁; 민병구; 이명철; 김성권; 이정상; 고창순
- Issue Date
- 서울대학교 의과대학
- Seoul J Med, Vol.24 No.4, pp. 437-441
- A new method for estimation of the renal functiolL
was developed using three-comparts model analysiswith
gamma camera system.
The rate constants of the plasma flows between
the compartments were obtained from the time
activity curves of three regions of interest (ROO.
the aorta, the left and right kidney.
The ratio of these rate constants was shown to
be proportional to the ratio of the glomerular Jletration rate (GFR) to the effective renal plasma
flow (ERPF), thus providing the estimated filtration
In 50 normal subjects, the ratio of the rate constants
(k 3/k, or k,/k,) was O. 19±0. 04 for left kidney
and O. 19±0. 05 for right kidney. In 25 patients with
abnormal renal function, these ratios were larger
than those in normal groups (0. 33±0. 09) or smaller
This method is simpler and more non-invasive
than other methods. And it provides a quantitative
evaluation method of the renal function.