만성신부전증에서 이뇨제가 청력에 미치는 영향에 관한 연구

Abstract

Fast infusion of small dose of furosemide produced acute transient mild hearing loss in cases of chronic renal dysfunction. Twenty-four cases were divided into 2 groups: In group 1, furosemide (60 mg) was infused intravenously into 15 cases (30 ears); in group 2, furosemide (120 rng) was infused intravenously into 9 cases C18 ears). Thirty minutes after injection of furosemide, the pure tone thresholds were measured using Belton 10 D audiometer and it was compared with the findings before and 24 hours after the injection. The results were as follows: I. Group 1: Pre-treated average threshold in all frequencies was 14.0 dB forming almost flat curve and post-treated value was 21. 3 dB in average in all frequencies with a difference of 7.3 dB. After 24 hours the threshold was returned to near pretreated value. 2. Group 2: Pre-treated average threshold in all frequencies was 18.0 dB with almost flat form and post-treated value was 31. 3 dB in all frequencies with the difference of 13 dB with slight decline in high frequencies. After 24 hours the threshold was returned to near pre-treated value.