각종 조직내에서의 연골의 생착비교

Abstract

Cartilage has been widely used as a autograft in plastic snrgery since the first such graft reputed to have been performed by Bert in 1865, but it is still not understood which tissues are best for preserving cartilage graft. The present work is a study of the fate of fresh autogenous cartilage grafted intradermally, just beneath the dermis. in the subcutaneous fat. and intramuscularly into the rabbit. In all experiments. 30 cases, adult non-Iittermate rabbits from a mixed stock were used. The rabbits were divided into 3 groups. Group I grafts were removed at postoperative 30 days. group II were at 60 days, group III were at 90 days. respectively and examined grossly and histologically. The following results were obtained; 1. The cartilage grafted intraderrnally were all absorbed grossly. 2. Even after 90 days the majority of the grafts appeared intact on naked-eye inspection. 3. Histologically the graft were normal and no evidence of cellular death or degeneration after 90 days. No change could be detected in the mucopolysaccharide of the cartilage ground substance during this period. Some degree of degeneration and new bone spicule formation were found. In these cases the absorbed cartilage were replaced by invasion of fibrous connective tissues.