Alloplastic Implant가 연골에 미치는 영향

Abstract

The phenomenon of alteration in solid tissues, such as bone appears sometimes when allaplastic implants are placed directly on this solid tissues. Bone changes beneath the alloplastic substance have not been described until 1969, when Robinson first reported this in humans. When the alloplastic implants are adjacent to cartilage. which is more softer than bone. it may be expected more complex reactions at the cellular level develop. The present work is a study of the cartilage change beneath the silastic implant in the rabbit ear. In all experiments, 30 cases, non-litterrnate rabbits from a mixed stock were used. Two silastic blocks, 10 x 5 x Imm in size, were implanted on the rabbit car cartilage. One was above the perichondrium and the other was below the perichondrium. All implants were removed 3 months after implantation. The cartilage beneath the implants were examined grossly and histologically. The following results were obtained; 1. On gross examination. the surface of the cartilage beneath the implants did not show any evidence of resorption. There was no difference between the supraperichondrial implantation and the subperichondrlal implantation during 3 months observation. 2. After the H-E, and PAS staining. and Anocarmine aniline blue modification the cartilages were examined histologically. The implants were surrounded by wellorganized fibrous capsule. The inner surfaces of the capsules were composed of mesothelium-like cell layer. Below the capsule the cartilage showed essentially implantnormal appearance whether the perichodrium protects the cartilage or not. And no change could be detected in the mucopolysaccharide of the cartilage ground substance during 3 months observation. 3. Further observation may necessiate to determine the ultimate effect upon the cartilage.