Browse

백혈병세포의 에너지대사
The Energy Metabolism of Leukemic Leukocytes.

Cited 0 time in Web of Science Cited 0 time in Scopus
Authors
박찬웅; 정명희; 김명석
Issue Date
1974-06
Publisher
서울대학교 의과대학
Citation
Seoul J Med, Vol.15 No.2, pp. 59-63
Abstract
The metabolism of the leukemic cells taken from
peripheral blood of patients with acute and chronic
lymphocytic leukemia and granulocytic leukemia
was determined manometrically with the Warburg
method.
Results can be summarized as follows.
1. Leukocytes taken from patients having acute
and chronic Iymphytic leukemia are characterized
by low aerobic glycolysis and low QAo'/QO, ratio.
Leukemic lymphocytes do not exhibit the so-called
"tumor-metabolism".
2. Granulocytic cells have high glycolytic rate and
high QAo'/QO, ratio and show incomplete Pasteur
effect.
3. Both leukemic lymphocytes and granulocytes
have the capacity for high glycolytic rates under
anaerobic conditions.
4. It seems that the metabolism of normal human
leukocyte is qualitatively similar to that of leukemic
counterparts.
5. It appears that both mature cells and blast
forms have same metabolic characteristics.
6. It is considered that to make conclusions
regarding the neoplastic nature of leukemia on the
basis of their tumor-metabolism is improper.
ISSN
0582-6802
Language
Korean
URI
https://hdl.handle.net/10371/7278
Files in This Item:
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 15 No.2 (1974)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse