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Plasma B-endorphin Levels in Patients Plasma B-endorphin Levels in Patients
자외선조사에 의한 표피 멜라닌 세포의 변화 및 일광차단제가 이에 미치는 영향 -조직화학적 및 초미세구조학적 연구

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Authors
Kim, Jung Gu; Chang, Yoon Seok; Lee, Jin Yong
Issue Date
1990-12
Publisher
Seoul National University College of Medicine
Citation
Seoul J Med, Vol.31 No.4, pp. 247-252
Keywords
Peripheral β-endorphinPolycystic ovarian diseaseObesity
Abstract
In order to determine endocrinologic changes by obesity in patients with
polycystic ovarian disease (PCOD) and to assess the involvement of peripheral ~-endorphin
in the pathogeneis of PCOD, levels of plasma ~-enorphin, gonadotropin. androgen
and prolactin were measured by radioimmunoassay. Thirty-one PCOD patients (21 normal
weight. 10 overweight) and 27 normally ovulating women. 20 normal weight. 7
overweight (normal controls) were studied. There were no significant differences in the
plasma gonadotropin, androgen, and prolactin levels between the overweight and normal
weight group in PCOD patients and normal controls. No significant difference
in plasma fJ-endorphin levels was found between normal weight controls and normal
weight patients. Plasma ~-endorphin levels were similar in overweight controls and
patients. These values were significantly higher than those in normal weight controls
and patients respectively. There was a significant correlation between plasma ~-endorphin
levels and the percentage of ideal body weight in patients with PCOD and normal
controls. These data suggest that peripheral opioid abnormality in PCOD may be a
phenomenon associated with obesity and not related to the pathogenesis of disease.
ISSN
0582-6802
Language
English
URI
http://hdl.handle.net/10371/7321
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College of Medicine/School of Medicine (의과대학/대학원)Dept. of Medicine (의학과)The Seoul Journal of MedicineThe Seoul Journal of Medicine Vol. 31 No.4 (1990)
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