S-Space College of Dentistry/School of Dentistry (치과대학/치의학대학원) Dept. of Dentistry (치의학과) Journal Papers (저널논문_치의학과)
In Vivo Study on the Biocompatibility of Newly Developed Calcium Phosphate-Based Root Canal Sealers
- Issue Date
- J Endodon 2004;30:708-711
- This study compared the biocompatibility of two new calcium phosphate-based root canal sealers (CAPSEAL I, CAPSEAL II) with another type of commercially available calcium phosphate sealer (Apatite Root Sealer type I, Apatite Root Sealer type II) and a zinc oxide eugenol-based sealer (Pulp Canal Sealer EWT) after implanting them in the subcutaneous tissue of rats. After 1, 2, 4, and 12 weeks, the tubes were removed with the surrounding tissues. The tissue reactions were graded as being mild or
1, moderate or 2, and severe or 3 after a histopathological
examination. The results were analyzed
statistically with the Kruskal-Wallis test. The
biocompatibility of the materials was interpreted
according to the Federation Dentaire Internationale
criteria (1980). The inflammatory reactions decreased
with time. The new sealers showed a
lower tissue response than any of the other sealers
in all the experimental periods. All the tested sealers
showed an acceptable biocompatibility.
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