Browse

Effect of hydroxyapatite-coated nanofibrous membrane on the responses of human periodontal ligament fibroblast

DC Field Value Language
dc.contributor.authorPark, Sun-Hye-
dc.contributor.authorKim, Tae-Il-
dc.contributor.authorKu, Young-
dc.contributor.authorChung, Chong-Pyoung-
dc.contributor.authorHan, Soo-Boo-
dc.contributor.authorYu, Ji-Hee-
dc.contributor.authorLee, Seung-Pyo-
dc.contributor.authorKim, Haw-Won-
dc.contributor.authorLee, Hae-Hyoung-
dc.date.accessioned2011-10-18T01:05:56Z-
dc.date.available2011-10-18T01:05:56Z-
dc.date.issued2008-01-
dc.identifier.citationJ. Ceramic Society of Japan, 116,31-35(2008)en
dc.identifier.issn1348-6535-
dc.identifier.urihttps://hdl.handle.net/10371/74250-
dc.description.abstractIn this study, hydroxyapatite-coated biopolymer nanofibrous membrane was synthesized by mineralizing the electrospun polycaprolactone nanofiber. The effect of the hydroxyapatite-coated nanofibrous membrane was mainly investigated on the proliferation and differentiation of human periodontal ligament fibroblast, which is necessary for periodontal tissue regeneration. Scanning electron microscopy revealed favorable cell attachment and spreading appearance on 1 d and MTS assay showed increased cell proliferation on the hydroxyapatite-coated nanofiber membrane during 14 d. From 7 to 14 d, alkaline phosphatase activity of the hydroxyapatite-coated nanofiber was significantly increased when compared to that of control group. Hydroxyapatite-coated nanofibrous membrane showed prominent mineral formation on day 14. As a result, it was clarified that the developed hydroxyapatite-coated nanofibrous membrane had favorable effects on the proliferation and differentiation of human periodontal ligament fibroblast and might be a good candidate material for periodontal tissue regeneration.en
dc.description.sponsorshipThis work was supported by Korea Research Foundation Grant funded by Korean Government(MOEHRD, Basic Research Promotion Fund)(KRF-2005-0003-E00255).en
dc.language.isoenen
dc.publisherCeramic Society of Japanen
dc.subjectBiomaterialen
dc.subjectHydroxyapatiteen
dc.subjectMembraneen
dc.subjectPeriodontal ligament fibroblasten
dc.subjectPeriodontal tissue regenerationen
dc.titleEffect of hydroxyapatite-coated nanofibrous membrane on the responses of human periodontal ligament fibroblasten
dc.typeArticleen
dc.contributor.AlternativeAuthor박선혜-
dc.contributor.AlternativeAuthor김태일-
dc.contributor.AlternativeAuthor구영-
dc.contributor.AlternativeAuthor정종평-
dc.contributor.AlternativeAuthor한수부-
dc.contributor.AlternativeAuthor유지희-
dc.contributor.AlternativeAuthor이승표-
dc.contributor.AlternativeAuthor김해원-
dc.contributor.AlternativeAuthor이해형-
Appears in Collections:
College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
Files in This Item:
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse