Browse

Biomimetic Approach to Dental Implants

Cited 0 time in Web of Science Cited 0 time in Scopus
Authors
Kim, Tae-Il; Jang, Jun-Hyeog; Kim, Hae-Won; Jonathan C. Knowles; Ku, Young
Issue Date
2008-08
Publisher
Bentham Science Publishers
Citation
Curr Pharm Des 2008;14(22):2201-11
Keywords
Biomimeticdental implantextracellular matrixosseointegrationtitanium
Abstract
Titanium, as an implant material, is regarded to be durable and biocompatible, which allows functional replacement of missing teeth. Successful dental implantation depends on an osseointegration phenomenon, a direct structural and functional binding reaction between bone and implant. It is well known that physicochemical characteristics of the dental implant surface, such as roughness, topography, chemistry, and electrical charge affect the biological reactions occurring at the interface of tissue and implant. Therefore, considerable efforts have been made to modify the surface of titanium implants which are based on mechanical, physical and chemical treatments. Recently, biological molecules were introduced onto the surface of implants to stimulate osteogenic cells in the early stage of implantation and consequently accelerate bone formation around implant and subsequent rapid implant stabilization. A range of extracellular matrix components, designed peptides, and growth factors have been proposed as the biological moiety. In this review, we address several issues related to the biology of dental implants and discuss biomimetic modification of the implant surface as a novel approach to obtain successful osseointegration.
ISSN
1381-6128
Language
English
URI
https://hdl.handle.net/10371/74277
Files in This Item:
There are no files associated with this item.
Appears in Collections:
College of Dentistry/School of Dentistry (치과대학/치의학대학원)Dept. of Dentistry (치의학과)Journal Papers (저널논문_치의학과)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse