S-Space College of Dentistry/School of Dentistry (치과대학/치의학대학원) Dept. of Dentistry (치의학과) Journal Papers (저널논문_치의학과)
수용성환원키토산 배합 양치액의 구취 형성 억제 효과 : Effect of water-soluble reduced chitosan on volatile sulfur compounds
- Issue Date
- J Korean Acad Dent Health 2009;33(3):339-345
- oral malodor ; volatile sulfur compounds ; water-soluble reduced chitosan ; 구취 ; 수용성환원키토산 ; 휘발성황화합물
- Objectives: This study examined the effects of newly developed water-soluble reduced chitosan on the
volatile sulfur compounds induced by 4-day plaque regrowth.
Methods: 1.0% water-soluble reduced chitosan with a pH ranging from 6.0 to 6.5, a molecular weight
between 3,000 and 5,000 Da, and a 70% of degree of deacetylation was used. The amounts of volatile
sulfur compounds in the mouth air were measured in vivo. Twelve dental students volunteered to
participate in this double blind, randomized, 4-day plaque regrowth study. The subjects were divided
into three groups and asked to rinse with the allocated mouthrinse solution and refraining from all
mechanical oral hygiene measures.
Results: The chitosan mouthwash reduced significantly the amounts of hydrogen sulfide in the mouth
air compared to DW.
Conclusions: The water-soluble reduced chitosan exhibited significant malodor-reducing activity
during the 4-day plaque regrowth experiment.