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Determination of the BMI threshold that predicts cardiovascular risk and insulin resistance in late childhood

Cited 8 time in Web of Science Cited 8 time in Scopus
Authors
Kim, Chanwon; Kim, Bomtaeck; Joo, Namseok; Park, Yongwoo; Ju, Youngsu; Park, Suekyung; Park, Kyunghee; Cho, Belong; Yang, Seiwon; Lim, Hyoungjune
Issue Date
2010
Publisher
ELSEVIER IRELAND LTD
Citation
DIABETES RESEARCH AND CLINICAL PRACTICE; Vol.88 3; 307-313
Keywords
Body mass indexCardiovascular riskInsulin resistanceThresholdChildhood
Abstract
Aims: Body mass index (BMI, kg/m(2)) thresholds of children predicting cardiovascular risk, reported in previous studies were inconsistent and that predicting increased insulin resistance is lacking. We determined the BMI threshold that predicts increased cardiovascular risk and insulin resistance in children. Methods: The entire 4th grade students (187 boys and 218 girls) from 5 schools were included. Cardiovascular risk was defined as the presence of three or more of cardiovascular risk factors. Increased insulin resistance was estimated using homeostasis model assessment of insulin resistance and fasting insulin level. Results: The BMI percentile predicting cardiovascular risk was the 71.3th percentile for boys and the 77.1th percentile for girls. The BMI value was 21.4 kg/m(2) for boys and 20.6 kg/m(2) for girls. 34% of boys and 42% of girls with a BMI above the cut-off values had cardiovascular risk. The BMI percentile predicting increased insulin resistance was the 66.3th percentile for boys and the 67.9th percentile for girls. The children with cardiovascular risk had significantly greater (P < 0.01) insulin resistance than those without risk. Conclusion: This study demonstrated that the BMI thresholds at which cardiovascular risk and insulin resistance begin to increase in Korean children were lower than current definition of childhood obesity, proposed by the international obesity task force. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
ISSN
0168-8227
Language
English
URI
https://hdl.handle.net/10371/76195
DOI
https://doi.org/10.1016/j.diabres.2010.02.005
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College of Medicine/School of Medicine (의과대학/대학원)Family Medicine (가정의학전공)Journal Papers (저널논문_가정의학전공)
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