Browse

The Mildly Elevated Serum Bilirubin Level is Negatively Associated with the Incidence of End Stage Renal Disease in Patients with IgA Nephropathy

DC Field Value Language
dc.contributor.authorChin, Ho Jun-
dc.contributor.authorCho, Hyun Jin-
dc.contributor.authorLee, Tae Woo-
dc.contributor.authorNa, Ki Young-
dc.contributor.authorJoo, Kwon Wook-
dc.contributor.authorKim, Yon-Su-
dc.contributor.authorHan, Jin Suk-
dc.contributor.authorJeon, En Sil-
dc.contributor.authorKim, Yong-Lim-
dc.contributor.authorLee, Sang Koo-
dc.contributor.authorLim, Chun Soo-
dc.contributor.authorOh, Yoon Kyu-
dc.contributor.authorLee, Jung Eun-
dc.contributor.authorKim, Yoon Goo-
dc.contributor.authorKim, Seong Gyun-
dc.contributor.authorSong, Young Rim-
dc.contributor.authorKim, Chan-Duck-
dc.contributor.authorPark, Sun-Hee-
dc.contributor.authorJo, Sang-Kyung-
dc.contributor.authorKim, Hyoung Kyu-
dc.contributor.authorCho, Won Yong-
dc.contributor.authorChae, Dong-Wan-
dc.contributor.authorJin, Dong Chan-
dc.contributor.authorKim, Suhnggwon-
dc.contributor.authorAhn, Curie-
dc.contributor.authorYoon, Hyung Jin-
dc.contributor.authorOh, Kook Hwan-
dc.date.accessioned2012-05-23T08:47:50Z-
dc.date.available2012-05-23T08:47:50Z-
dc.date.issued2009-01-
dc.identifier.citationJOURNAL OF KOREAN MEDICAL SCIENCE; Vol.24 ; S22-S29ko_KR
dc.identifier.issn1011-8934-
dc.identifier.urihttps://hdl.handle.net/10371/76353-
dc.description.abstractOxidative stress plays various roles in the development and progression of IgA nephropathy, while bilirubin is known as a potent antioxidant. We therefore hypothesized that serum bilirubin would be associated with renal prognosis in IgA nephropathy. The study subjects comprised 1,458 adult patients with primary IgA nephropathy in Korea. We grouped patients according to the following quartile levels of bilirubin: <0.4 mg/dL (Q1), 0.4-0.5 mg/dL (Q2),0.6-0.7 mg/dL (Q3), and >0.8 mg/dL (Q4). The outcome data were obtained from the Korean Registry of end-stage renal disease (ESRD). Eighty patients (5.5%) contracted ESRD during a mean follow-up period of 44.9 months. The ESRD incidences were 10.7% in Q1, 8.2% in Q2, 2.8% in Q3, and 2.8% in 04 (p<0.001). The relative risk of ESRD compared to that in Q1 was 0.307 (95% confidence interval [CI], 0.126-0.751) in Q3 and 0.315 (95% CI, 0.130-0.765) in Q4. The differences of ESRD incidence were greater in subgroups of males and of patients aged 35 yr or more, with serum albumin 4.0 g/dL or more, with normotension, with eGFR 60 mL/min/1.73 m(2) or more, and with proteinuria less then 3+ by dipstick test. In conclusion, higher bilirubin level was negatively associated with ESRD incidence in IgA nephropathy.ko_KR
dc.language.isoenko_KR
dc.publisherKOREAN ACAD MEDICAL SCIENCESko_KR
dc.subjectBilirubinko_KR
dc.subjectKidney Failureko_KR
dc.subjectGlomerulonephritisko_KR
dc.subjectChronicko_KR
dc.subjectIGAko_KR
dc.titleThe Mildly Elevated Serum Bilirubin Level is Negatively Associated with the Incidence of End Stage Renal Disease in Patients with IgA Nephropathyko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor진호준-
dc.contributor.AlternativeAuthor조현진-
dc.contributor.AlternativeAuthor이태우-
dc.contributor.AlternativeAuthor나기영-
dc.contributor.AlternativeAuthor오국환-
dc.contributor.AlternativeAuthor주권욱-
dc.contributor.AlternativeAuthor윤형진-
dc.contributor.AlternativeAuthor김연수-
dc.contributor.AlternativeAuthor안규리-
dc.contributor.AlternativeAuthor한진숙-
dc.contributor.AlternativeAuthor김성권-
dc.contributor.AlternativeAuthor전은실-
dc.contributor.AlternativeAuthor진동찬-
dc.contributor.AlternativeAuthor김용림-
dc.contributor.AlternativeAuthor박선희-
dc.contributor.AlternativeAuthor김찬덕-
dc.contributor.AlternativeAuthor송영림-
dc.contributor.AlternativeAuthor김성균-
dc.contributor.AlternativeAuthor김윤구-
dc.contributor.AlternativeAuthor이정은-
dc.contributor.AlternativeAuthor오윤규-
dc.contributor.AlternativeAuthor임춘수-
dc.contributor.AlternativeAuthor이상구-
dc.contributor.AlternativeAuthor채동완-
dc.contributor.AlternativeAuthor조원용-
dc.contributor.AlternativeAuthor김형규-
dc.contributor.AlternativeAuthor조상경-
dc.identifier.doi10.3346/jkms.2009.24.S1.S22-
dc.citation.journaltitleJOURNAL OF KOREAN MEDICAL SCIENCE-
dc.description.citedreferenceLiu YR, 2008, J IMMUNOL, V181, P1887-
dc.description.citedreferenceMoranne O, 2008, QJM-INT J MED, V101, P215, DOI 10.1093/qjmed/hcm142-
dc.description.citedreferenceLIN LY, 2008, ATHEROSCLEROSIS 0726-
dc.description.citedreferenceKobori H, 2007, BIOCHEM BIOPH RES CO, V358, P156, DOI 10.1016/j.bbrc.2007.04.105-
dc.description.citedreferenceKirkby K, 2007, AM J PHYSIOL-RENAL, V292, pF888, DOI 10.1152/ajprenal.00064.2006-
dc.description.citedreferenceLee SW, 2005, YONSEI MED J, V46, P658-
dc.description.citedreferenceLanone S, 2005, FASEB J, V19, P1890, DOI 10.1096/fj.04-2683fje-
dc.description.citedreferenceBarratt J, 2005, J AM SOC NEPHROL, V16, P2088-
dc.description.citedreferenceLevey AS, 2005, KIDNEY INT, V67, P2089-
dc.description.citedreferenceSharma K, 2005, AM J PHYSIOL-RENAL, V288, pF1069, DOI 10.1152/ajprenal.00345.2004-
dc.description.citedreferenceAdin CA, 2005, AM J PHYSIOL-RENAL, V288, pF778, DOI 10.1152/ajprenal.00215.2004-
dc.description.citedreferencePflueger A, 2005, AM J PHYSIOL-RENAL, V288, pF552, DOI 10.1152/ajprenal.00278.2004-
dc.description.citedreferenceNakao A, 2005, AM J TRANSPLANT, V5, P282, DOI 10.1111/j.1600-6143.2004.00695.x-
dc.description.citedreferenceDescamps-Latscha B, 2004, KIDNEY INT, V66, P1606-
dc.description.citedreferenceToth B, 2003, ARCH SURG-CHICAGO, V138, P1375-
dc.description.citedreferenceKitada M, 2003, DIABETES, V52, P2603-
dc.description.citedreferenceKim SY, 2003, NEPHROLOGY, V8, pS2-
dc.description.citedreferenceLi JM, 2003, J AM SOC NEPHROL, V14, pS221, DOI 10.1097/01.ASN.0000077406.67663.E7-
dc.description.citedreferenceEndler G, 2003, CLIN CHEM, V49, P1201-
dc.description.citedreferenceNovotny L, 2003, EXP BIOL MED, V228, P568-
dc.description.citedreferenceDonadio JV, 2002, NEW ENGL J MED, V347, P738-
dc.description.citedreferenceRadford MG, 1997, J AM SOC NEPHROL, V8, P199-
dc.description.citedreferenceTuri S, 1997, FREE RADICAL BIO MED, V22, P161-
dc.description.citedreferenceThannickal VJ, 1995, J BIOL CHEM, V270, P30334-
dc.description.citedreferenceIBELS LS, 1994, MEDICINE, V73, P79-
dc.description.citedreferenceMANOLIO TA, 1992, CLIN CHEM, V38, P1853-
dc.description.citedreferenceCHEN HC, 1992, J CLIN LAB ANAL, V6, P35-
dc.description.citedreferenceSTOCKER R, 1987, SCIENCE, V235, P1043-
dc.description.citedreferenceSANO K, 1985, PEDIATR RES, V19, P587-
dc.description.citedreferenceSCHMID R, 1965, NATURE, V206, P1041-
dc.description.tc6-
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
Files in This Item:
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse