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The targeting of endothelial progenitor cells to a specific location within a microfluidic channel using magnetic nanoparticles

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dc.contributor.authorKim, Jeong Ah-
dc.contributor.authorLee, Hong Jai-
dc.contributor.authorKang, Hyun-Jae-
dc.contributor.authorPark, Tai Hyun-
dc.date.accessioned2012-05-24T01:53:43Z-
dc.date.available2012-05-24T01:53:43Z-
dc.date.issued2009-02-
dc.identifier.citationBIOMEDICAL MICRODEVICES; Vol.11 1; 287-296ko_KR
dc.identifier.issn1387-2176-
dc.identifier.urihttps://hdl.handle.net/10371/76382-
dc.description.abstractA common problem with the in vivo therapeutic applications of cells is that cells can rapidly disappear into the circulatory system after an injection. Magnetic nanoparticles can be used to solve this problem. Bacterial magnetic nanoparticles were used in this study for targeting stem cells at a specific location within a microfluidic channel. Magnetic nanoparticles were isolated from Magnetospirillum sp. AMB-1 and delivered to endothelial progenitor cells (EPCs). Cellular uptake of magnetic nanoparticles and their functional feasibility was characterized in vitro. The environment of a human blood vessel was simulated using a microfluidic channel. Magnetic nanoparticle-incorporated EPCs were injected into a microchannel and the flow rate of cells was uniformly controlled by use of a syringe pump. EPCs were effectively targeted to a specific location within the microchannel by an external magnetic field (about 400 mT). About 40% of EPCs were efficiently targeted with a flow rate of 5 mu l min(-1) when 10 mu g of magnetic nanoparticles were used per 10(4) cells. This microfluidic system provides a useful tool towards a better understanding of the behavior of magnetic nanoparticle-incorporated cells within the human circulatory system for clinical use.ko_KR
dc.language.isoenko_KR
dc.publisherSPRINGERko_KR
dc.subjectMagnetic nanoparticleko_KR
dc.subjectEndothelial progenitor cellko_KR
dc.subjectCirculatory systemko_KR
dc.subjectMicrofluidic systemko_KR
dc.titleThe targeting of endothelial progenitor cells to a specific location within a microfluidic channel using magnetic nanoparticlesko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor김정아-
dc.contributor.AlternativeAuthor이홍재-
dc.contributor.AlternativeAuthor강현재-
dc.contributor.AlternativeAuthor박태현-
dc.identifier.doi10.1007/s10544-008-9235-y-
dc.citation.journaltitleBIOMEDICAL MICRODEVICES-
dc.description.citedreferenceChung YC, 2008, BIOMATERIALS, V29, P1807, DOI 10.1016/j.biomaterials.2007.12.032-
dc.description.citedreferenceKopp RE, 2008, EARTH-SCI REV, V86, P42, DOI 10.1016/j.earscirev.2007.08.001-
dc.description.citedreferenceWilhelm C, 2007, BIOMATERIALS, V28, P3797, DOI 10.1016/j.biomaterials.2007.04.047-
dc.description.citedreferenceKim JA, 2007, BIOSENS BIOELECTRON, V22, P3273, DOI 10.1016/j.bios.2007.02.009-
dc.description.citedreferencePisanic TR, 2007, BIOMATERIALS, V28, P2572, DOI 10.1016/j.biomaterials.2007.01.043-
dc.description.citedreferenceTakeda S, 2007, J MAGN MAGN MATER, V311, P367, DOI 10.1016/j.jmmm.2006.10.1195-
dc.description.citedreferenceChoi D, 2007, BIOTECHNOL BIOPROC E, V12, P39-
dc.description.citedreferenceKRICEVSKY A, 2007, J APPL PHYS, V101-
dc.description.citedreferenceJurgons R, 2006, J PHYS-CONDENS MAT, V18, pS2893, DOI 10.1088/0953-8984/18/38/S24-
dc.description.citedreferenceKim YS, 2006, BIOTECHNOL BIOPROC E, V11, P449-
dc.description.citedreferenceKim JA, 2006, BIOCHEM ENG J, V29, P91, DOI 10.1016/j.bej.2005.02.032-
dc.description.citedreferenceKomeili A, 2006, SCIENCE, V311, P242, DOI 10.1126/science.1123231-
dc.description.citedreferenceYoon CH, 2005, CIRCULATION, V112, P1618, DOI 10.1161/CIRCULATIONAHA.104.503433-
dc.description.citedreferenceSong JW, 2005, ANAL CHEM, V77, P3993, DOI 10.1021/ac050131o-
dc.description.citedreferenceGupta AK, 2005, BIOMATERIALS, V26, P1565, DOI 10.1016/j.biomaterials.2004.05.022-
dc.description.citedreferenceRitter JA, 2004, J MAGN MAGN MATER, V280, P184, DOI 10.1016/j.jmmm.2004.03.012-
dc.description.citedreferenceKang HJ, 2004, CAN MED ASSOC J, V171, P442-
dc.description.citedreferenceWeiss BP, 2004, EARTH PLANET SC LETT, V224, P73, DOI [10.1016/j.epsl.2004.04.024, 10.1016/j.espl.2004.04.024]-
dc.description.citedreferenceVerma S, 2004, CIRCULATION, V109, P2058, DOI 10.1161/01.CIR.0000127577.63323.24-
dc.description.citedreferenceHur J, 2004, ARTERIOSCL THROM VAS, V24, P288, DOI 10.1161/01.ATV.0000114236.77009.06-
dc.description.citedreferenceFRANKEL RB, 2004, NANOBIOTECHNOLOGY, P136-
dc.description.citedreferenceGulati R, 2003, CIRC RES, V93, P1023, DOI 10.1161/01.RES.0000105569.77539.21-
dc.description.citedreferencePankhurst QA, 2003, J PHYS D APPL PHYS, V36, pR167, DOI 10.1088/0022-3727/36/13/201-
dc.description.citedreferenceHristov M, 2003, TRENDS CARDIOVAS MED, V13, P201-
dc.description.citedreferenceKawamoto A, 2003, CIRCULATION, V107, P461, DOI 10.1161/01.CIR.0000046450.89986.50-
dc.description.citedreferencePARK TH, 2003, BIOTECHNOL PROGR, V19, P43-
dc.description.citedreferenceSakakibara M, 2002, ARTERIOSCL THROM VAS, V22, P1360, DOI 10.1161/01.ATV.0000027102.53875.47-
dc.description.citedreferenceWilhelm C, 2002, EUR BIOPHYS J BIOPHY, V31, P118, DOI 10.1007/s00249-001-0200-4-
dc.description.citedreferenceLyden D, 2001, NAT MED, V7, P1194-
dc.description.citedreferenceKawamoto A, 2001, CIRCULATION, V103, P634-
dc.description.citedreferenceSeong S, 2001, BIOTECHNOL BIOENG, V76, P11-
dc.description.citedreferenceKubo T, 2000, INT J ONCOL, V17, P309-
dc.description.citedreferenceKalka C, 2000, P NATL ACAD SCI USA, V97, P3422-
dc.description.citedreferenceGoodwin S, 1999, J MAGN MAGN MATER, V194, P132-
dc.description.citedreferenceBulte JWM, 1999, JMRI-J MAGN RESON IM, V9, P329-
dc.description.citedreferenceAsahara T, 1997, SCIENCE, V275, P964-
dc.description.citedreferenceJordan A, 1996, INT J HYPERTHER, V12, P705-
dc.description.citedreferenceUSAMI S, 1993, ANN BIOMED ENG, V21, P77-
dc.description.citedreferenceNAKAMURA N, 1991, ANAL CHEM, V63, P268-
dc.description.citedreferenceSTARK DD, 1988, RADIOLOGY, V168, P297-
dc.description.citedreferenceGORBY YA, 1988, J BACTERIOL, V170, P843-
dc.description.citedreferenceSTECHELL CH, 1985, J CHEM TECHNOL BIO B, V35, P175-
dc.description.citedreferencePATTERSON MK, 1979, METHOD ENZYMOL, V58, P141-
dc.description.tc12-
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