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Assessment of Subclinical Coronary Atherosclerosis in Asymptomatic Patients With Type 2 Diabetes Mellitus With Single Photon Emission Computed Tomography and Coronary Computed Tomography Angiography
DC Field | Value | Language |
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dc.contributor.author | Choi, Eue-Keun | - |
dc.contributor.author | Chun, Eun Ju | - |
dc.contributor.author | Choi, Sang-Il | - |
dc.contributor.author | Chang, Sung-A | - |
dc.contributor.author | Lim, Soo | - |
dc.contributor.author | Nasir, Khurram | - |
dc.contributor.author | Jang, Hak-Chul | - |
dc.contributor.author | Chang, Hyuk-Jae | - |
dc.contributor.author | Blumenthal, Roger S. | - |
dc.contributor.author | Rivera, Juan J. | - |
dc.contributor.author | Choi, Sung-Hee | - |
dc.date.accessioned | 2012-05-24T06:25:05Z | - |
dc.date.available | 2012-05-24T06:25:05Z | - |
dc.date.issued | 2009-10-01 | - |
dc.identifier.citation | AMERICAN JOURNAL OF CARDIOLOGY; Vol.104 7; 890-896 | ko_KR |
dc.identifier.issn | 0002-9149 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76423 | - |
dc.description.abstract | We evaluated the characteristics of coronary artery disease in asymptomatic patients with type 2 diabetes mellitus (DM) using single photon emission computed tomography (SPECT) and coronary computed tomographic angiography (CCTA). A total of 116 patients with DM without abnormal electrocardiographic findings or evidence of peripheral arterial disease (number of risk factors >= 2; 62 +/- 7 years, 59% men) underwent CCTA and SPECT. Of the 116 patients with DM, 88 (76%) had a normal single photon emission computed tomographic findings, and 28 (24%) had abnormal perfusion defects. Of the 116 patients, 92 (79%) had atherosclerotic plaques (2 +/- 2 segments per subject), and 20 (17%) had significant stenosis seen on CCTA. Patients with DM and normal findings on SPECT had a similar prevalence of atherosclerotic plaque (78% vs 82% significant stenosis (15% vs 25%), severe stenosis (7% vs 7% and calcified (40% vs 43% mixed (49% vs 57% and noncalcified plaques (26% vs 29%) and a high (> 100) coronary artery calcium score (32% vs 29%; all p >0.05) compared to those with abnormal findings on SPECT. During the mid-term follow-up (24 +/- 4 months), 5 cardiac events occurred in patients with DM and normal findings on SPECT, only in those with occult CAD on CCTA: 1 sudden cardiac death and 4 revascularization procedures. In conclusion, a significant percentage of patients with DM and normal eletrocardiographic findings, no peripheral arterial disease, and normal findings on SPECT have evidence of occult CAD on CCTA. Furthermore, a small percentage had had a cardiac event by mid-term follow-up. SPECT showed limited capability to differentiate the coronary risks between patients with DM and no coronary plaque and from those with a certain degree of disease; 2 circumstances that represent different coronary risks. (C) 2009 Elsevier Inc. All rights reserved. (Am J Cardiol 2009;104:890-896) | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC | ko_KR |
dc.title | Assessment of Subclinical Coronary Atherosclerosis in Asymptomatic Patients With Type 2 Diabetes Mellitus With Single Photon Emission Computed Tomography and Coronary Computed Tomography Angiography | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 최유근 | - |
dc.contributor.AlternativeAuthor | 천은주 | - |
dc.contributor.AlternativeAuthor | 최상일 | - |
dc.contributor.AlternativeAuthor | 장성아 | - |
dc.contributor.AlternativeAuthor | 최성희 | - |
dc.contributor.AlternativeAuthor | 임수 | - |
dc.contributor.AlternativeAuthor | 장학철 | - |
dc.contributor.AlternativeAuthor | 장혁재 | - |
dc.identifier.doi | 10.1016/j.amjcard.2009.05.026 | - |
dc.citation.journaltitle | AMERICAN JOURNAL OF CARDIOLOGY | - |
dc.description.citedreference | Young LH, 2009, JAMA-J AM MED ASSOC, V301, P1547, DOI 10.1001/jama.2009.476 | - |
dc.description.citedreference | Rivera JJ, 2009, ATHEROSCLEROSIS, V203, P442, DOI 10.1016/j.atherosclerosis.2008.07.030 | - |
dc.description.citedreference | Schomig A, 2008, J AM COLL CARDIOL, V52, P894, DOI 10.1016/j.jacc.2008.05.051 | - |
dc.description.citedreference | Choi EK, 2008, J AM COLL CARDIOL, V52, P357, DOI 10.1016/j.jacc.2008.02.086 | - |
dc.description.citedreference | Scholte AJHA, 2008, J NUCL CARDIOL, V15, P503, DOI 10.1016/j.nuclcard.2008.02.015 | - |
dc.description.citedreference | Diamond GA, 2007, J AM COLL CARDIOL, V49, P1915, DOI 10.1016/j.jacc.2006.09.057 | - |
dc.description.citedreference | Boden WE, 2007, NEW ENGL J MED, V356, P1503 | - |
dc.description.citedreference | Romeo F, 2007, AM J CARDIOL, V99, P325, DOI 10.1016/j.amjcard.2006.08.029 | - |
dc.description.citedreference | Anand DV, 2006, EUR HEART J, V27, P713, DOI 10.1093/eurheartj/ehi808 | - |
dc.description.citedreference | Leber AW, 2006, J AM COLL CARDIOL, V47, P672, DOI 10.1016/j.jacc.2005.10.058 | - |
dc.description.citedreference | Rajagopalan N, 2005, J AM COLL CARDIOL, V45, P43, DOI 10.1016/j.jacc.2004.06.078 | - |
dc.description.citedreference | Abidov A, 2004, J NUCL MED, V45, P1999 | - |
dc.description.citedreference | Wackers FJT, 2004, DIABETES CARE, V27, P1954 | - |
dc.description.citedreference | Zellweger MJ, 2004, EUR HEART J, V25, P543, DOI 10.1016/j.ehj.2004.02.013 | - |
dc.description.citedreference | Lawlor DA, 2003, J EPIDEMIOL COMMUN H, V57, P538, DOI 10.1136/jech.57.7.538 | - |
dc.description.citedreference | Hachamovitch R, 2003, J AM COLL CARDIOL, V41, P1329, DOI 10.1016/S0735-1097(03)00125-6 | - |
dc.description.citedreference | Sobel BE, 2003, CIRCULATION, V107, P636 | - |
dc.description.citedreference | 2002, CIRCULATION, V106, P3143 | - |
dc.description.citedreference | Giri S, 2002, CIRCULATION, V105, P32 | - |
dc.description.citedreference | BELLER GA, 1999, J NUCL CARDIOL, V6, P93 | - |
dc.description.citedreference | Hachamovitch R, 1996, CIRCULATION, V93, P905 | - |
dc.description.citedreference | AGATSTON AS, 1990, J AM COLL CARDIOL, V15, P827 | - |
dc.description.citedreference | AUSTEN WG, 1975, CIRCULATION S, V51, P5 | - |
dc.description.tc | 5 | - |
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