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Sarcopenic Obesity: Prevalence and Association With Metabolic Syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA)

Cited 332 time in Web of Science Cited 329 time in Scopus
Authors
Lim, Soo; Kim, Jung Hee; Yoon, Ji Won; Kang, Seon Mee; Park, Young Joo; Lim, Jae Young; Jang, Hak Chul; Park, Kyong Soo; Kim, Ki Woong; Choi, Sung Hee
Issue Date
2010-07
Publisher
AMER DIABETES ASSOC
Citation
DIABETES CARE; Vol.33 7; 1652-1654
Abstract
OBJECTIVE - We investigated the prevalence of sarcopenic obesity (SO) and its relationship with metabolic syndrome in a community-based elderly cohort in Korea. RESEARCH DESIGN AND METHODS - In this study, 287 men and 278 women aged 65 or older were recruited. Sarcopenia was defined as the appendicular skeletal muscle mass (ASM) divided by height squared (Ht(2)) (kg/m(2)) or by weight (Wt) (%) of <1 SD below the sex-specific mean for young adults. Obesity was defined as a visceral fat area >= 100 cm(2). RESULTS - The prevalence of SO was 16.7% in men and 5.7% in women with sarcopenia defined by ASM/Ht(2); however, it was 35.1% in men and 48.1% in women by ASM/Wt. Using ASM/Wt, the homeostasis model assessment of insulin resistance of subjects with SO was higher and they were at higher risk for metabolic syndrome (odds ratio [OR] 8.28 [95% Cl 4.45-15.40]) than the obese (5.51 [2.81-10.80]) or sarcopenic group (2.64 [1.08-6.44]). CONCLUSIONS - SO defined by ASM/Wt was more closely associated with metabolic syndrome than either sarcopenia or obesity alone.
ISSN
0149-5992
Language
English
URI
https://hdl.handle.net/10371/76489
DOI
https://doi.org/10.2337/dc10-0107
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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