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Incidence and Outcomes of Contrast-Induced Nephropathy After Computed Tomography in Patients With CKD: A Quality Improvement Report
DC Field | Value | Language |
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dc.contributor.author | Kim, Sun Moon | - |
dc.contributor.author | Cha, Ran-hui | - |
dc.contributor.author | Lee, Jung Pyo | - |
dc.contributor.author | Kim, Dong Ki | - |
dc.contributor.author | Joo, Kwon Wook | - |
dc.contributor.author | Kim, Suhnggwon | - |
dc.contributor.author | Kim, Yon Su | - |
dc.contributor.author | Lim, Chun Soo | - |
dc.contributor.author | Oh, Kook-Hwan | - |
dc.date.accessioned | 2012-05-25T08:56:31Z | - |
dc.date.available | 2012-05-25T08:56:31Z | - |
dc.date.issued | 2010-06 | - |
dc.identifier.citation | AMERICAN JOURNAL OF KIDNEY DISEASES; Vol.55 6; 1018-1025 | ko_KR |
dc.identifier.issn | 0272-6386 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76498 | - |
dc.description.abstract | Background: Although there has been considerable investigation of the general characteristics of contrast-induced nephropathy (CIN), it has not been studied adequately in a computed tomography (CT) population. We assessed the incidence and outcomes of CIN after contrast-enhanced CT in patients with chronic kidney disease pretreated with saline and N-acetylcysteine (NAC). Design: Quality improvement report. Setting & Participants: 520 patients registered in a CIN prevention program. Quality Improvement Plan: We initiated the CIN prevention program in January 2007. In this program, patients with chronic kidney disease undergoing contrast-enhanced CT in an outpatient setting were automatically referred to nephrologists, and patients received saline and NAC before and after CT. The development of CIN was assessed 48-96 hours after CT. Outcomes: Incidence of CIN and time to renal replacement therapy. Measurements: Baseline serum creatinine, hemoglobin, and serum albumin levels; type and volume of contrast agents; and post-CT serum creatinine level. Results: Overall, CIN occurred in 13 (2.5%) patients. Incidences of CIN were 0.0%, 2.9%, and 12.1% in patients with an estimated glomerular filtration rate of 45-59, 30-44, and <30 mL/min/1.73 m(2), respectively. The risk of CIN was increased in patients with severely decreased kidney function and diabetes. The development of CIN consequently increased the risk of renal replacement therapy (P < 0.001 by log-rank), and the risk was significantly accentuated in patients with estimated glomerular filtration rate <30 mL/min/1.73 m(2). Limitations: A single-center study and comparison with previous studies. Conclusions: The incidence of CIN was relatively low in patients treated with saline and NAC. The development of CIN predisposed to poor kidney survival in the long term. Am J Kidney Dis 55: 1018-1025. (C) 2010 by the National Kidney Foundation, Inc. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | W B SAUNDERS CO-ELSEVIER INC | ko_KR |
dc.subject | Acute kidney injury | ko_KR |
dc.subject | chronic kidney disease | ko_KR |
dc.subject | saline | ko_KR |
dc.subject | N-acetylcysteine | ko_KR |
dc.subject | contrast-induced nephropathy | ko_KR |
dc.title | Incidence and Outcomes of Contrast-Induced Nephropathy After Computed Tomography in Patients With CKD: A Quality Improvement Report | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김선문 | - |
dc.contributor.AlternativeAuthor | 차란희 | - |
dc.contributor.AlternativeAuthor | 이정표 | - |
dc.contributor.AlternativeAuthor | 김동기 | - |
dc.contributor.AlternativeAuthor | 오국환 | - |
dc.contributor.AlternativeAuthor | 조권욱 | - |
dc.contributor.AlternativeAuthor | 임춘수 | - |
dc.contributor.AlternativeAuthor | 김성권 | - |
dc.contributor.AlternativeAuthor | 김연수 | - |
dc.identifier.doi | 10.1053/j.ajkd.2009.10.057 | - |
dc.citation.journaltitle | AMERICAN JOURNAL OF KIDNEY DISEASES | - |
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dc.description.tc | 3 | - |
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