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Subclinical hypothyroidism (SCH) is not associated with metabolic derangement, cognitive impairment, depression or poor quality of life (QoL) in elderly subjects

Cited 65 time in Web of Science Cited 66 time in Scopus
Authors
Park, Young Joo; Lee, Eun Jung; Lee, You Jin; Choi, Sung Hee; Lee, Seok Bum; Lee, Won Woo; Cho, Bo Youn; Kim, Ki Woong; Woo, Jong Inn; Jang, Hak C.; Lim, Soo; Park, Joon Hyuk
Issue Date
2010-06
Publisher
ELSEVIER IRELAND LTD
Citation
ARCHIVES OF GERONTOLOGY AND GERIATRICS; Vol.50 3; E68-E73
Keywords
Subclinical hypothyroidismMetabolic dysfunction in elderlyNeuropsychological function
Abstract
The objective of this study was to examine the relationship between SCH and metabolic and neuropsychiatric derangements in Korean elderly subjects. Nine hundred and eighteen euthyroid and SCH subjects aged 65 years and older were enrolled in the present study. We compared anthropometric (age, sex, blood pressure, body mass index = BMI, body fat contents = BF, waist circumference = WC and hip circumference = HC), laboratory (glucose and lipid profile, renal and liver functions, and C-reactive protein = CRP levels), and neuropsychiatric (neuropsychological function, mood, and QoL) parameters of SCH subjects with those of euthyroid subjects. Associated metabolic disorders of the subjects were also compared between the euthyroid and SCH groups. We could not observe any differences between the SCH group and the euthyroid group with regards to metabolic parameters as well as neuropsychiatric parameters. These findings may suggest that SCH does not appear to be associated with metabolic and neuropsychiatric derangement in elderly subjects. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
ISSN
0167-4943
Language
English
URI
http://hdl.handle.net/10371/76553
DOI
https://doi.org/10.1016/j.archger.2009.05.015
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College of Medicine/School of Medicine (의과대학/대학원)Internal Medicine (내과학전공)Journal Papers (저널논문_내과학전공)
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