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Intraamniotic infection with genital mycoplasmas exhibits a more intense inflammatory response than intraamniotic infection with other microorganisms in patients with preterm premature rupture of membranes

Cited 80 time in Web of Science Cited 86 time in Scopus
Authors
Oh, Kyung Joon; Lee, Kyung A.; Sohn, Yoo-Kyung; Park, Chan-Wook; Romero, Roberto; Yoon, Bo Hyun; Hong, Joon-Seok
Issue Date
2010-09
Publisher
MOSBY-ELSEVIER
Citation
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY; Vol.203 3; -
Keywords
chorioamnionitispreterm birthureaplasmamycoplasmasinterleukin-6IL-6intraamniotic inflammationCRP
Abstract
OBJECTIVE: The objective of the study was to compare the intensity of inflammatory responses between intraamniotic infection with genital mycoplasmas and intraamniotic infection with other microorganisms. STUDY DESIGN: We examined the intensity of intraamniotic and maternal inflammatory responses in 99 patients with preterm premature rupture of membranes and a positive amniotic fluid (AF) culture. AF was obtained by transabdominal amniocentesis or at the time of cesarean delivery. Patients were divided according to the recovered microorganisms: (1) genital mycoplasmas (n = 62); (2) other microorganisms (n = 31); or (3) mixed infection (n = 6). RESULTS: The median AF white blood cell (WBC) count, maternal blood WBC count, and plasma C-reactive protein concentrations were significantly higher in patients with intraamniotic infection with genital mycoplasmas than in those with intraamniotic infection with other microorganisms (P < .05 for each). CONCLUSION: Intraamniotic and maternal inflammatory responses are more intense in intraamniotic infection with genital mycoplasmas than in intraamniotic infection with other microorganisms in patients with preterm premature rupture of membranes.
ISSN
0002-9378
Language
English
URI
https://hdl.handle.net/10371/76793
DOI
https://doi.org/10.1016/j.ajog.2010.03.035
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College of Medicine/School of Medicine (의과대학/대학원)Obstetrics & Gynecology (산부인과전공)Journal Papers (저널논문_산부인과학전공)
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