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Wine drinking and epithelial ovarian cancer risk: a meta-analysis
DC Field | Value | Language |
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dc.contributor.author | Kim, Hee Seung | - |
dc.contributor.author | Kim, Jae Weon | - |
dc.contributor.author | Shouten, Leo J. | - |
dc.contributor.author | Larsson, Susanna C. | - |
dc.contributor.author | Kim, Yong Beom | - |
dc.contributor.author | Park, Noh Hyun | - |
dc.contributor.author | Kim, Seung Cheol | - |
dc.contributor.author | Kang, Soon-Beom | - |
dc.contributor.author | Song, Yong Sang | - |
dc.contributor.author | Ju, Woong | - |
dc.contributor.author | Chung, Hyun Hoon | - |
dc.date.accessioned | 2012-06-05T00:15:19Z | - |
dc.date.available | 2012-06-05T00:15:19Z | - |
dc.date.issued | 2010-06 | - |
dc.identifier.citation | JOURNAL OF GYNECOLOGIC ONCOLOGY; Vol.21 2; 112-118 | ko_KR |
dc.identifier.issn | 2005-0380 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76813 | - |
dc.description.abstract | Objective: Wine has been the focus in the prevention of epithelial ovarian cancer (EOC) development because resveratrol abundant in wine has anti-carcinogenic properties. However, epidemiologic results have been heterogenous in the chemopreventive effect of wine on the development of EOC. Thus, we performed a meta-analysis for comparing EOC risk between wine and never drinkers using previous related studies. Methods: After extensive search of the literature between January 1986 and December 2008, we analyzed 10 studies (3 cohort and 7 case control studies) with 135,871 women, who included 65,578 of wine and 70,293 of never drinkers. Results: In all studies, there was no significant difference in EOC risk between wine and never drinkers (odds ratio [OR], 1.13; 95% confidence interval [CI], 0.92 to 1.38; random effects). When we performed re-analysis according to the study design, 3 cohort and 7 case control studies showed that there were also no significant differences in EOC risk between wine and never drinkers, respectively (OR, 1.44 and 1.04; 95% CI, 0.74 and 2.82 and 0.88 to 1.22; random effects). In sub-analyses using 2 case-control studies, EOC risk was not different between former and never drinkers (OR, 1.12; 95% CI, 0.87 to 1.44; fixed effect), and between current and former drinkers (OR, 0.74; 95% CI, 0.41 to 1.34; random effects). Conclusion: Although resveratrol, abundantly found in wine, is a promising naturally occurring compound with chemopreventive properties on EOC in preclinical studies, this meta-analysis suggests the epiderniologic evidence shows no association between wine drinking and EOC risk. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | KOREAN SOC GYNECOLOGY ONCOLOGY & COLPOSCOPY | ko_KR |
dc.subject | Wine | ko_KR |
dc.subject | Resveratrol | ko_KR |
dc.subject | Epithelial ovarian cancer | ko_KR |
dc.title | Wine drinking and epithelial ovarian cancer risk: a meta-analysis | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 김희승 | - |
dc.contributor.AlternativeAuthor | 김재원 | - |
dc.contributor.AlternativeAuthor | 정현훈 | - |
dc.contributor.AlternativeAuthor | 김용범 | - |
dc.contributor.AlternativeAuthor | 주웅 | - |
dc.contributor.AlternativeAuthor | 박노현 | - |
dc.contributor.AlternativeAuthor | 송용상 | - |
dc.contributor.AlternativeAuthor | 김승철 | - |
dc.contributor.AlternativeAuthor | 강순범 | - |
dc.identifier.doi | 10.3802/jgo.2010.21.2.112 | - |
dc.citation.journaltitle | JOURNAL OF GYNECOLOGIC ONCOLOGY | - |
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dc.description.tc | 1 | - |
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