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Paclitaxel- Versus Sirolimus-Eluting Stents for Treatment of ST-Segment Elevation Myocardial Infarction With Analyses for Diabetic and Nondiabetic Subpopulation
DC Field | Value | Language |
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dc.contributor.author | Cho, Youngjin | - |
dc.contributor.author | Yang, Han-Mo | - |
dc.contributor.author | Park, Kyung-Woo | - |
dc.contributor.author | Chung, Woo-Young | - |
dc.contributor.author | Seo, Won-Woo | - |
dc.contributor.author | Chae, Sung-Chul | - |
dc.contributor.author | Hur, Seung-Ho | - |
dc.contributor.author | Seong, In-Whan | - |
dc.contributor.author | Oh, Suk-Kyu | - |
dc.contributor.author | Jeong, Myung-Ho | - |
dc.contributor.author | Kim, Young-Jo | - |
dc.contributor.author | Cho, Myeong-Chan | - |
dc.contributor.author | Hong, Taeg-Jong | - |
dc.contributor.author | Bae, Jang-Ho | - |
dc.contributor.author | Jang, Yang-Soo | - |
dc.contributor.author | Rha, Seung-Woon | - |
dc.contributor.author | Park, Keum-Soo | - |
dc.contributor.author | Kim, Doo-Il | - |
dc.contributor.author | Kim, Hyo-Soo | - |
dc.contributor.author | Chae, In-Ho | - |
dc.contributor.author | Park, Sue K. | - |
dc.contributor.author | Kim, Min-Jung | - |
dc.contributor.author | Yoon, Jung-Han | - |
dc.contributor.author | Chae, Jei-Keon | - |
dc.contributor.author | Lee, Myoung-Yong | - |
dc.contributor.author | Jeong, Kyoung-Tae | - |
dc.contributor.author | Choi, Dong-Joo | - |
dc.date.accessioned | 2012-06-07T08:58:47Z | - |
dc.date.available | 2012-06-07T08:58:47Z | - |
dc.date.issued | 2010-05 | - |
dc.identifier.citation | JACC-CARDIOVASCULAR INTERVENTIONS; Vol.3 5; 498-506 | ko_KR |
dc.identifier.issn | 1936-8798 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76885 | - |
dc.description.abstract | Objectives The aim of this study was to determine which drug-eluting stent (DES) is preferable for the treatment of ST-segment elevation myocardial infarction (STEMI) and to elucidate the impact of diabetes mellitus on the outcome of each DES. Background Recent studies have shown the benefit of DES in patients with STEMI. Diabetes mellitus might differentially affect outcomes of each DES. Methods We analyzed the large-scale, prospective, observational KAMIR (Korea Acute Myocardial Infarction Registry) study, which enrolled 4,416 STEMI patients (26% with diabetes) treated with paclitaxel-eluting stent (PES) or sirolimus-eluting stent (SES). Primary outcome was major adverse cardiac event (MACE), defined as a composite of mortality, nonfatal myocardial infarction, and target lesion revascularization (TLR). Results In the overall population, the MACE rate at 1 year was significantly higher in the PES than the SES group (11.6% vs. 8.6%, p = 0.014), which was mainly due to increased TLR (3.7% vs. 1.8%, p < 0.001). In the diabetic subgroup, however, the MACE rate was not significantly different between PES and SES (14.5% vs. 12.3%, p = 0.217), in contrast to the nondiabetic subgroup, where PES was inferior to SES as in the overall population. Matching by propensity-score did not significantly alter these results. For TLR, there was interaction between the type of stents and diabetes mellitus (unadjusted: p = 0.052; after propensity-score matching: p = 0.035). Conclusions The PES was inferior to the SES in the overall population, with regard to the occurrence of MACE and TLR. However, subgroup analysis for diabetic subjects showed no differences in clinical outcomes between PES and SES. These results suggest that diabetes differentially affects the outcome of first-generation DES. (J Am Coll Cardiol Intv 2010;3:498-506) (C) 2010 by the American College of Cardiology Foundation | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | ELSEVIER SCIENCE INC | ko_KR |
dc.subject | diabetes mellitus | ko_KR |
dc.subject | stents | ko_KR |
dc.subject | myocardial infarction | ko_KR |
dc.title | Paclitaxel- Versus Sirolimus-Eluting Stents for Treatment of ST-Segment Elevation Myocardial Infarction With Analyses for Diabetic and Nondiabetic Subpopulation | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 조영진 | - |
dc.contributor.AlternativeAuthor | 양한모 | - |
dc.contributor.AlternativeAuthor | 박경우 | - |
dc.contributor.AlternativeAuthor | 정우영 | - |
dc.contributor.AlternativeAuthor | 최동주 | - |
dc.contributor.AlternativeAuthor | 서원우 | - |
dc.contributor.AlternativeAuthor | 정경태 | - |
dc.contributor.AlternativeAuthor | 채성철 | - |
dc.contributor.AlternativeAuthor | 이명용 | - |
dc.contributor.AlternativeAuthor | 허승호 | - |
dc.contributor.AlternativeAuthor | 최재건 | - |
dc.contributor.AlternativeAuthor | 성인환 | - |
dc.contributor.AlternativeAuthor | 윤정한 | - |
dc.contributor.AlternativeAuthor | 오석규 | - |
dc.contributor.AlternativeAuthor | 김두일 | - |
dc.contributor.AlternativeAuthor | 박금수 | - |
dc.contributor.AlternativeAuthor | 나승운 | - |
dc.contributor.AlternativeAuthor | 장양수 | - |
dc.contributor.AlternativeAuthor | 배장호 | - |
dc.contributor.AlternativeAuthor | 홍택종 | - |
dc.contributor.AlternativeAuthor | 조명찬 | - |
dc.contributor.AlternativeAuthor | 김영조 | - |
dc.contributor.AlternativeAuthor | 정명호 | - |
dc.contributor.AlternativeAuthor | 김민정 | - |
dc.contributor.AlternativeAuthor | 박수경 | - |
dc.contributor.AlternativeAuthor | 채인호 | - |
dc.contributor.AlternativeAuthor | 김효수 | - |
dc.identifier.doi | 10.1016/j.jcin.2010.02.011 | - |
dc.citation.journaltitle | JACC-CARDIOVASCULAR INTERVENTIONS | - |
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dc.description.tc | 0 | - |
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