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Antioxidant Vitamins Intake, Ataxia Telangiectasia Mutated (ATM) Genetic Polymorphisms, and Breast Cancer Risk
DC Field | Value | Language |
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dc.contributor.author | Lee, Sang-Ah | - |
dc.contributor.author | Lee, Kyoung-Mu | - |
dc.contributor.author | Lee, Seung-Joon | - |
dc.contributor.author | Yoo, Keun-Young | - |
dc.contributor.author | Noh, Dong-Young | - |
dc.contributor.author | Kang, Daehee | - |
dc.contributor.author | Ahn, Sei-Hyun | - |
dc.contributor.author | Park, Sue Kyung | - |
dc.date.accessioned | 2012-06-08T06:35:17Z | - |
dc.date.available | 2012-06-08T06:35:17Z | - |
dc.date.issued | 2010 | - |
dc.identifier.citation | NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL; Vol.62 8; 1087-1094 | ko_KR |
dc.identifier.issn | 0163-5581 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76909 | - |
dc.description.abstract | Ataxia telangiectasia mutated (ATM) cells exist under a constant state of oxidative stress with high levels of reactive oxygen species, which are removed by cellular antioxidant vitamins. We investigated the independent and combined effect of antioxidant vitamins intake and the ATM genotype or diplotype on the breast cancer risk. Analyses included 323 cases and age-matched controls who participated in the Korean Breast Cancer Study during 2001-2003 with complete dietary information. The vitamin A (P 0.01) and -tocopherol (P 0.01) were associated with lower breast cancer risk as well as some water-soluble vitamins including vitamin B2 (P = 0.01), vitamin C (P 0.01), and folic acid (P = 0.02) intake. No five single nucleotide polymorphisms (ATM-5144A T (rs228589), IVS21 + 1049T C (rs664677), IVS33-55T C (rs664982), IVS34+60G A (rs664143), and 3393T G (rs4585)) studied showed significant differences in their allele frequencies between the cases and controls. On the other hand, compared with the diploid of ATTGT/ATTGT, as the number of ATTGT haplotype decreased, the risk of breast cancer increased (P = 0.04). The association between ATM diplotype and the breast cancer risk was predominantly among women with low intake of antioxidant vitamins including vitamin A, vitamin C, and folic acid. This study suggested that some antioxidant vitamins intake may modify the effect of ATM diplotype on the breast cancer risk among Korean women. | ko_KR |
dc.description.sponsorship | This research was supported by the BRL (Basic Research
Laboratory) program through theNational Research Foundation of Korea funded by the Ministry of Education, Science and Technology (2009-0087452). | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | LAWRENCE ERLBAUM ASSOC INC-TAYLOR & FRANCIS | ko_KR |
dc.title | Antioxidant Vitamins Intake, Ataxia Telangiectasia Mutated (ATM) Genetic Polymorphisms, and Breast Cancer Risk | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 이상아 | - |
dc.contributor.AlternativeAuthor | 이경무 | - |
dc.contributor.AlternativeAuthor | 이승준 | - |
dc.contributor.AlternativeAuthor | 유근영 | - |
dc.contributor.AlternativeAuthor | 박수경 | - |
dc.contributor.AlternativeAuthor | 노동영 | - |
dc.contributor.AlternativeAuthor | 안세현 | - |
dc.contributor.AlternativeAuthor | 강대희 | - |
dc.identifier.doi | 10.1080/01635581.2010.492088 | - |
dc.citation.journaltitle | NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL | - |
dc.description.citedreference | Kabat GC, 2008, BRIT J CANCER, V99, P816, DOI 10.1038/sj.bjc.6604540 | - |
dc.description.citedreference | *NAT CANC INF CTR, 2008, REP NAT CANC INF CTR | - |
dc.description.citedreference | Michels KB, 2007, CANCER, V109, P2712, DOI 10.1002/cncr.22654 | - |
dc.description.citedreference | Erker L, 2006, FREE RADICAL BIO MED, V41, P590, DOI 10.1016/j.freeradbiomed.2006.04.032 | - |
dc.description.citedreference | Bingham S, 2006, P NUTR SOC, V65, P19, DOI 10.1079/PNS2005472 | - |
dc.description.citedreference | Powers HJ, 2005, J NUTR, V135, p2960S | - |
dc.description.citedreference | Lee KM, 2005, CANCER EPIDEM BIOMAR, V14, P821 | - |
dc.description.citedreference | Kim YI, 2004, CANCER EPIDEM BIOMAR, V13, P511 | - |
dc.description.citedreference | Sommer SS, 2003, CANCER GENET CYTOGEN, V145, P115, DOI 10.1016/S0165-4608(03)00119-5 | - |
dc.description.citedreference | Bretsky P, 2003, CANCER EPIDEM BIOMAR, V12, P733 | - |
dc.description.citedreference | Dutta A, 2003, J AM COLL NUTR, V22, P258 | - |
dc.description.citedreference | LEE SA, 2003, J KOREAN BREAST CANC, V6, P271 | - |
dc.description.citedreference | Marcelain K, 2002, REV MED CHILE, V130, P957 | - |
dc.description.citedreference | de Jong MM, 2002, J MED GENET, V39, P225 | - |
dc.description.citedreference | Barzilai A, 2002, DNA REPAIR, V1, P3 | - |
dc.description.citedreference | BERNSTEIN JL, 2002, BREAST CANCER RES, V4, P249 | - |
dc.description.citedreference | SPURDLE AB, 2002, BREAST CANCER RES, V4, pNIL49 | - |
dc.description.citedreference | Benhar M, 2001, MOL CELL BIOL, V21, P6913 | - |
dc.description.citedreference | Ames BN, 2001, MUTAT RES-FUND MOL M, V475, P7, DOI 10.1016/S0027-5107(01)00070-7 | - |
dc.description.citedreference | Kamsler A, 2001, CANCER RES, V61, P1849 | - |
dc.description.citedreference | Shiloh Y, 2001, BIOCHEM SOC T, V29, P661 | - |
dc.description.citedreference | Takao N, 2000, FEBS LETT, V472, P133 | - |
dc.description.citedreference | Gandini S, 2000, EUR J CANCER, V36, P636, DOI 10.1016/S0959-8049(00)00022-8 | - |
dc.description.citedreference | Reichenbach J, 1999, CLIN EXP IMMUNOL, V117, P535 | - |
dc.description.citedreference | Barlow C, 1999, P NATL ACAD SCI USA, V96, P9915 | - |
dc.description.citedreference | Rotman G, 1997, BIOESSAYS, V19, P911 | - |
dc.description.citedreference | *WORLD CANC RES FU, 1997, FOOD NUTR PREV CANC | - |
dc.description.citedreference | Shiloh Y, 1997, ANNU REV GENET, V31, P635 | - |
dc.description.citedreference | Barlow C, 1996, CELL, V86, P159 | - |
dc.description.citedreference | SAVITSKY K, 1995, SCIENCE, V268, P1749 | - |
dc.description.citedreference | KEY T, 1994, P NUTR SOC, V53, P605 | - |
dc.description.citedreference | EASTON DF, 1994, BRIT MED BULL, V50, P527 | - |
dc.description.tc | 2 | - |
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