Publications
Detailed Information
Cancer incidence among paraquat-exposed pesticide applicators in the Agricultural Health Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Sue K. | - |
dc.contributor.author | Kang, Daehee | - |
dc.contributor.author | Beane-Freeman, Laura | - |
dc.contributor.author | Blair, Aaron | - |
dc.contributor.author | Sandler, Dale P. | - |
dc.contributor.author | Knott, Charles | - |
dc.contributor.author | Alavanja, Michael | - |
dc.contributor.author | Gwak, Jin | - |
dc.contributor.author | Lynch, Charles F. | - |
dc.contributor.author | Hoppin, Jane A. | - |
dc.date.accessioned | 2012-06-08T07:44:08Z | - |
dc.date.available | 2012-06-08T07:44:08Z | - |
dc.date.issued | 2009-09 | - |
dc.identifier.citation | INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH; Vol.15 3; 274-281 | ko_KR |
dc.identifier.issn | 1077-3525 | - |
dc.identifier.uri | https://hdl.handle.net/10371/76924 | - |
dc.description.abstract | Paraquat (1,1`-dimethyl-4, 4`-bipyridinium dichloride) is a nonselective herbicide that is extremely toxic after acute exposure. It was once widely used in North America and is still used in some countries, including the United States. Although there is little firm evidence that paraquat is a carcinogen, previous Studies have suggested a potential relationship with some cancers. This prospective cohort Study was performed to evaluate the association between lifetime paraquat exposure and cancer incidence among licensed pesticide applicators with 9.1 years of median follow-up. The lifetime ever-use of paraquat was evaluated in 56,224 subjects at baseline and exposure-response relationship was evaluated in 24,667 subjects (44%) who provided detailed information on total life-time paraquat exposure in a second questionnaire. Among the total subjects, the risk for non-Hodgkin`s lymphoma (NHL) in the exposed group was marginally elevated (Relative risk [RR], 1.47; 95% confidence interval [CI], 0.97-2.23) compared to the non-exposed group. However, among the 24,667 applicators who Supplied total life-time exposure days, the highest tertile of lifetime exposure-days (LE) and intensity-weighted lifetime exposure-days (IWLE) was not significantly associated with NHL risk (RR, 1.57; 95%CI, 0.57-4.23 for LE; RR, 1.42; 95%CI, 0.40-4.71 for IWLE, respectively) and there was no significant exposure-response trend (p-trend > 0.1). There was Some suggestion of a possible link between paraquat exposure and NHL risk in humans, but die inconsistency in exposure level trend suggests that this could be a chance finding. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | ABEL PUBLICATION SERVICES | ko_KR |
dc.subject | Paraquat | ko_KR |
dc.subject | Agricultural Health Study | ko_KR |
dc.subject | cancer incidence | ko_KR |
dc.subject | non-Hodgkin`s lymphoma | ko_KR |
dc.title | Cancer incidence among paraquat-exposed pesticide applicators in the Agricultural Health Study | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 박수경 | - |
dc.contributor.AlternativeAuthor | 강대희 | - |
dc.contributor.AlternativeAuthor | 곽진 | - |
dc.citation.journaltitle | INTERNATIONAL JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH | - |
dc.description.citedreference | Cerhan JR, 2008, CANCER EPIDEM BIOMAR, V17, P3161, DOI 10.1158/1055-9965.EPI-08-0536 | - |
dc.description.citedreference | Engels EA, 2008, INT J CANCER, V123, P187, DOI 10.1002/ijc.23487 | - |
dc.description.citedreference | Yang W, 2008, J TOXICOL ENV HEAL A, V71, P289, DOI 10.1080/15287390701738467 | - |
dc.description.citedreference | KEGLEY S, 2008, PAN PESTICIDE DATABA | - |
dc.description.citedreference | LEE K, 2008, INT ARCH OCC ENV HEA, V82, P455 | - |
dc.description.citedreference | Monge P, 2007, SCAND J WORK ENV HEA, V33, P293 | - |
dc.description.citedreference | Vineis P, 2007, CANCER EPIDEM BIOMAR, V16, P381, DOI 10.1158/1055-9965.EPI-07-0124 | - |
dc.description.citedreference | Yang W, 2007, J TOXICOL ENV HEAL A, V70, P1849, DOI 10.1080/15287390701459262 | - |
dc.description.citedreference | Bloom SE, 2006, TOXICOL SCI, V89, P214, DOI 10.1093/toxsci/kfj021 | - |
dc.description.citedreference | D`Souza UJA, 2005, MUTAT RES-GEN TOX EN, V581, P187, DOI 10.1016/j.mrgentox.2004.10.019 | - |
dc.description.citedreference | Muller AMS, 2005, ANN HEMATOL, V84, P1, DOI 10.1007/s00277-004-0939-7 | - |
dc.description.citedreference | LEE WJ, 2005, OCCUP ENVIRON MED, V62, P786 | - |
dc.description.citedreference | WESSELING C, 2005, TOXICOL APPL PHARM, V207, pS697 | - |
dc.description.citedreference | Weidauer E, 2004, TOXICOL LETT, V151, P69, DOI 10.1016/j.toxlet.2004.02.014 | - |
dc.description.citedreference | Takeyama N, 2004, INT J TOXICOL, V23, P33, DOI 10.1080/10915810490265432 | - |
dc.description.citedreference | Ambrus A, 2003, PURE APPL CHEM, V75, P937 | - |
dc.description.citedreference | Hoppin JA, 2002, J EXPO ANAL ENV EPID, V12, P313, DOI 10.1038/sj.jea.7500232 | - |
dc.description.citedreference | Dosemeci M, 2002, ANN OCCUP HYG, V46, P245, DOI 10.1093/annhyg/mef011 | - |
dc.description.citedreference | Blair A, 2002, EPIDEMIOLOGY, V13, P94 | - |
dc.description.citedreference | WESSELING C, 2001, INT J OCCUP ENV HEAL, V7, P275 | - |
dc.description.citedreference | Wesseling C, 1999, INT J EPIDEMIOL, V28, P365 | - |
dc.description.citedreference | REIGART JR, 1999, RECOGNITION MANAGEME, P108 | - |
dc.description.citedreference | Dusinska M, 1998, CARCINOGENESIS, V19, P809 | - |
dc.description.citedreference | Tarone RE, 1997, AM J IND MED, V31, P233 | - |
dc.description.citedreference | *US EPA, 1997, R E D FACTS PAR DICH | - |
dc.description.citedreference | Ribas G, 1997, TERATOGEN CARCIN MUT, V17, P339 | - |
dc.description.citedreference | Wesseling C, 1996, INT J EPIDEMIOL, V25, P1125 | - |
dc.description.citedreference | Blair A, 1995, ENVIRON HEALTH PERSP, V103, P205 | - |
dc.description.citedreference | JEE SH, 1995, INT J DERMATOL, V34, P466 | - |
dc.description.citedreference | HALL AH, 1995, PARAQUAT POISONING M, P249 | - |
dc.description.citedreference | WINCHESTER JF, 1995, DRUG CH TOX, V10, P1 | - |
dc.description.citedreference | SALAM AZE, 1993, MUTAT RES, V319, P89 | - |
dc.description.citedreference | KUO ML, 1993, MUTAT RES, V300, P223 | - |
dc.description.citedreference | JAWORSKA A, 1991, INT J RADIAT BIOL, V60, P899 | - |
dc.description.citedreference | PERCY C, 1990, INT CLASSIFICATION D | - |
dc.description.citedreference | LIN JL, 1990, CLIN MED TAIWAN, V26, P352 | - |
dc.description.citedreference | MINCHIN RF, 1989, LIFE SCI, V45, P63 | - |
dc.description.citedreference | WANG JD, 1987, BRIT J IND MED, V44, P196 | - |
dc.description.citedreference | VALE JA, 1987, HUM TOXICOL, V6, P41 | - |
dc.description.citedreference | *INT PROGR CHEM SA, 1984, ENV HLTH CRIT, V39 | - |
dc.description.citedreference | ROSS WE, 1979, BIOCHEM BIOPH RES CO, V91, P1302 | - |
dc.description.citedreference | *US CDCP, FACTS AB PAR | - |
dc.description.tc | 0 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.