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Cerebellum Can Be a Possible Generator of Progressive Myoclonus

Cited 11 time in Web of Science Cited 12 time in Scopus
Authors
Koh, Kyung Nam; Lim, Byung Chan; Hwang, Hee; Park, June Dong; Kim, Ki Joong; Kim, Seung-Ki; Moon, Han Ku; Wang, Kyu-Chang; Hwang, Yong-Seung; Chae, Jong Hee
Issue Date
2010-06
Publisher
SAGE PUBLICATIONS INC
Citation
JOURNAL OF CHILD NEUROLOGY; Vol.25 6; 728-731
Keywords
cerebellar gangliogliomainvasive electroencephalographymyoclonus
Abstract
A 19-month-old girl presented with progressive myoclonic jerking of both proximal lower extremities. On her brain magnetic resonance imaging (MRI), the authors found an ill-defined mass involving cerebellar vermis and the right middle cerebellar peduncle. (11)C-methionine positron emission tomography (PET) showed no abnormalities, but (18)F-fluorodeoxyglucose ((18)F-FDG) PET revealed a well-defined hypermetabolic focus. Depth electrodes were inserted deep into the mass, which recorded focal slow waves associated with the clinical myoclonus. Following the removal of the tumor, the myoclonus was completely resolved with no neurological deficit. Here, the authors present a case showing progressive myoclonus associated with a cerebellar ganglioglioma with the electrophysiological data, which provides strong supportive evidence that the cerebellum can be a myoclonus generator.
ISSN
0883-0738
Language
English
URI
http://hdl.handle.net/10371/76977
DOI
https://doi.org/10.1177/0883073809342273
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College of Medicine/School of Medicine (의과대학/대학원)Pediatrics (소아과학전공)Journal Papers (저널논문_소아과학전공)
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