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Reproducible and persistent weakness in adult rats after surgical resection of motor cortex: evaluation with limb placement test

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dc.contributor.authorLee, Do-Hun-
dc.contributor.authorHong, Seok Ho-
dc.contributor.authorKim, Seung-Ki-
dc.contributor.authorLee, Chang-Sub-
dc.contributor.authorCho, Byung-Kyu-
dc.contributor.authorWang, Kyu-Chang-
dc.contributor.authorPhi, Ji Hoon-
dc.date.accessioned2012-06-13T08:59:27Z-
dc.date.available2012-06-13T08:59:27Z-
dc.date.issued2009-12-
dc.identifier.citationCHILDS NERVOUS SYSTEM; Vol.25 12; 1547-1553ko_KR
dc.identifier.issn0256-7040-
dc.identifier.urihttps://hdl.handle.net/10371/77048-
dc.description.abstractThe purpose of this study was to develop a new rat model for surgical brain injury with motor weakness and to find an adequate behavior test for the application of the model. Thirty rats were divided into three groups: craniectomy (n = 10), durotomy (n = 10), and corticectomy (n = 10) groups. The coordinates of the three points from the bregma (coordinate A = +4,+1, B = -2,+1, and C = +4,+6). We evaluated right limb motor performance by the modified limb placement test and the cylinder test. Persistent motor weakness was observed for 2 months in the corticectomy group by the limb placement test, whereas the cylinder test could not detect the weakness. We established a reproducible and persistent rat brain injury model and found that the modified limb placement test is sensitive enough to evaluate residual subtle weakness in this model.ko_KR
dc.language.isoenko_KR
dc.publisherSPRINGERko_KR
dc.subjectCorticectomyko_KR
dc.subjectRatko_KR
dc.subjectFunctional recoveryko_KR
dc.subjectMotor cortexko_KR
dc.subjectMotor weaknessko_KR
dc.subjectLimb placement testko_KR
dc.titleReproducible and persistent weakness in adult rats after surgical resection of motor cortex: evaluation with limb placement testko_KR
dc.typeArticleko_KR
dc.contributor.AlternativeAuthor이도훈-
dc.contributor.AlternativeAuthor홍석호-
dc.contributor.AlternativeAuthor김승기-
dc.contributor.AlternativeAuthor이창섭-
dc.contributor.AlternativeAuthor피지훈-
dc.contributor.AlternativeAuthor조병규-
dc.contributor.AlternativeAuthor왕규창-
dc.identifier.doi10.1007/s00381-009-0973-9-
dc.citation.journaltitleCHILDS NERVOUS SYSTEM-
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College of Medicine/School of Medicine (의과대학/대학원)Neurosurgery (신경외과학전공)Journal Papers (저널논문_신경외과학전공)
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