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Reproducible and persistent weakness in adult rats after surgical resection of motor cortex: evaluation with limb placement test
DC Field | Value | Language |
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dc.contributor.author | Lee, Do-Hun | - |
dc.contributor.author | Hong, Seok Ho | - |
dc.contributor.author | Kim, Seung-Ki | - |
dc.contributor.author | Lee, Chang-Sub | - |
dc.contributor.author | Cho, Byung-Kyu | - |
dc.contributor.author | Wang, Kyu-Chang | - |
dc.contributor.author | Phi, Ji Hoon | - |
dc.date.accessioned | 2012-06-13T08:59:27Z | - |
dc.date.available | 2012-06-13T08:59:27Z | - |
dc.date.issued | 2009-12 | - |
dc.identifier.citation | CHILDS NERVOUS SYSTEM; Vol.25 12; 1547-1553 | ko_KR |
dc.identifier.issn | 0256-7040 | - |
dc.identifier.uri | https://hdl.handle.net/10371/77048 | - |
dc.description.abstract | The purpose of this study was to develop a new rat model for surgical brain injury with motor weakness and to find an adequate behavior test for the application of the model. Thirty rats were divided into three groups: craniectomy (n = 10), durotomy (n = 10), and corticectomy (n = 10) groups. The coordinates of the three points from the bregma (coordinate A = +4,+1, B = -2,+1, and C = +4,+6). We evaluated right limb motor performance by the modified limb placement test and the cylinder test. Persistent motor weakness was observed for 2 months in the corticectomy group by the limb placement test, whereas the cylinder test could not detect the weakness. We established a reproducible and persistent rat brain injury model and found that the modified limb placement test is sensitive enough to evaluate residual subtle weakness in this model. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | SPRINGER | ko_KR |
dc.subject | Corticectomy | ko_KR |
dc.subject | Rat | ko_KR |
dc.subject | Functional recovery | ko_KR |
dc.subject | Motor cortex | ko_KR |
dc.subject | Motor weakness | ko_KR |
dc.subject | Limb placement test | ko_KR |
dc.title | Reproducible and persistent weakness in adult rats after surgical resection of motor cortex: evaluation with limb placement test | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 이도훈 | - |
dc.contributor.AlternativeAuthor | 홍석호 | - |
dc.contributor.AlternativeAuthor | 김승기 | - |
dc.contributor.AlternativeAuthor | 이창섭 | - |
dc.contributor.AlternativeAuthor | 피지훈 | - |
dc.contributor.AlternativeAuthor | 조병규 | - |
dc.contributor.AlternativeAuthor | 왕규창 | - |
dc.identifier.doi | 10.1007/s00381-009-0973-9 | - |
dc.citation.journaltitle | CHILDS NERVOUS SYSTEM | - |
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dc.description.tc | 0 | - |
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