S-Space College of Medicine/School of Medicine (의과대학/대학원) Neurosurgery (신경외과학전공) Journal Papers (저널논문_신경외과학전공)
Effects of Mn concentration on the ac magnetically induced heating characteristics of superparamagnetic Mn(x)Zn(1-x)Fe(2)O(4) nanoparticles for hyperthermia
- Jeun, Minhong; Moon, Seung Je; Kobayashi, Hiroki; Shin, Hye Young; Kim, Yu Jeong; Paek, Sun Ha; Chung, Kyung-Won; Bae, Seongtae; Park, Ki Ho; Takemura, Yasushi; Tomitaka, Asahi
- Issue Date
- AMER INST PHYSICS
- APPLIED PHYSICS LETTERS; Vol.96 20;202511
- The effects of Mn(2+) cation concentration on the ac magnetically induced heating characteristics and the magnetic properties of superparamagnetic Mn(x)Zn(1-x)Fe(2)O(4) nanoparticles (SPNPs) were investigated to explore the biotechnical feasibility as a hyperthermia agent. Among the Mn(x)Zn(1-x)Fe(2)O(4) SPNPs, the Mn(0.5)Zn(0.5)Fe(2)O(4) SPNP showed the highest ac magnetically induced heating temperature (Delta T(ac,mag)), the highest specific absorption rate (SAR), and the highest biocompatibility. The higher out of phase susceptibility (chi(``)(m)) value and the higher chemical stability systematically controlled by the replacement of Zn(2+) cations by the Mn(2+) cations on the A-site (tetrahedral site) are the primary physical reason for the promising biotechnical properties of Mn(0.5)Zn(0.5)Fe(2)O(4) SPNP.