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Expression of neuronal antigens and related ventral and dorsal proteins in the normal spinal cord and a surgically induced open neural tube defect of the spine in chick embryos: an immunohistochemical study
DC Field | Value | Language |
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dc.contributor.author | Lee, Do-Hun | - |
dc.contributor.author | Phi, Ji Hoon | - |
dc.contributor.author | Chung, You-Nam | - |
dc.contributor.author | Lee, Yun-Jin | - |
dc.contributor.author | Cho, Byung-Kyu | - |
dc.contributor.author | Park, Moon-Sik | - |
dc.contributor.author | Wang, Kyu-Chang | - |
dc.contributor.author | Kim, Dong Won | - |
dc.contributor.author | Kim, Seung-Ki | - |
dc.date.accessioned | 2012-06-14T01:23:24Z | - |
dc.date.available | 2012-06-14T01:23:24Z | - |
dc.date.issued | 2010-05 | - |
dc.identifier.citation | CHILDS NERVOUS SYSTEM; Vol.26 5; 627-636 | ko_KR |
dc.identifier.issn | 0256-7040 | - |
dc.identifier.uri | https://hdl.handle.net/10371/77062 | - |
dc.description.abstract | The aims of this study were to elucidate the processes of neuronal differentiation and ventrodorsal patterning in the spinal cord of the chick embryo from embryonic day (E) 3 to E17 and to study the effect of a prenatal spinal open neural tube defect (ONTD) on these processes. Expression patterns of neuronal antigens (neuronal nuclear antigen, neurofilament-associated protein (NAP), and synaptophysin) and related ventral markers [sonic hedgehog, paired box gene (PAX)6, and islet-1], and dorsal markers (bone morphogenetic protein, Notch homolog 1, and PAX7) were investigated in the normal spinal cord and in a surgically induced spinal ONTD in chick embryos. Four normal and ONTD chick embryos were used for each antigen group. There were no differences in the expression of neuronal and ventrodorsal markers between the control and ONTD groups. NAP and synaptophysin were useful for identifying dorsal structures in the distorted anatomy of the ONTD chicks. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | SPRINGER | ko_KR |
dc.subject | Spinal cord | ko_KR |
dc.subject | Chick embryo | ko_KR |
dc.subject | Ventral and dorsal markers | ko_KR |
dc.subject | Neuron | ko_KR |
dc.subject | Open neural tube defect | ko_KR |
dc.title | Expression of neuronal antigens and related ventral and dorsal proteins in the normal spinal cord and a surgically induced open neural tube defect of the spine in chick embryos: an immunohistochemical study | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 이도훈 | - |
dc.contributor.AlternativeAuthor | 피지훈 | - |
dc.contributor.AlternativeAuthor | 정유남 | - |
dc.contributor.AlternativeAuthor | 이윤진 | - |
dc.contributor.AlternativeAuthor | 김승기 | - |
dc.contributor.AlternativeAuthor | 조병규 | - |
dc.contributor.AlternativeAuthor | 김동원 | - |
dc.contributor.AlternativeAuthor | 박문식 | - |
dc.contributor.AlternativeAuthor | 왕규창 | - |
dc.identifier.doi | 10.1007/s00381-009-1049-6 | - |
dc.citation.journaltitle | CHILDS NERVOUS SYSTEM | - |
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dc.description.tc | 0 | - |
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