Publications
Detailed Information
Changes in Prostate-specific Antigen Levels and Prostate Volume in Octogenarian Men: Community-based Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chung, Jae Seung | - |
dc.contributor.author | Byun, Seok-Soo | - |
dc.contributor.author | Han, Byung Kyu | - |
dc.contributor.author | Jeong, Seong Jin | - |
dc.contributor.author | Lee, Sang Eun | - |
dc.contributor.author | Hong, Sung Kyu | - |
dc.date.accessioned | 2012-06-15T00:26:41Z | - |
dc.date.available | 2012-06-15T00:26:41Z | - |
dc.date.issued | 2009-06 | - |
dc.identifier.citation | UROLOGY; Vol.73 6; 1270-1273 | ko_KR |
dc.identifier.issn | 0090-4295 | - |
dc.identifier.uri | https://hdl.handle.net/10371/77093 | - |
dc.description.abstract | OBJECTIVES To examine the change in prostate-specific antigen (PSA) levels and prostate volume (PV) in octogenarian men compared with those in septuagenarian men and evaluate the possibility of PSA as a surrogate marker for PV in octogenarian men. METHODS A total of 441 men were recruited from whom random and selected oldest-old samples (age >= 85 years) from the Korean Longitudinal Study on Health and Aging, which was a population-based, prospective cohort study on health, aging, and common geriatric diseases of Koreans >= 65 years old. Men in their 70s (n = 136, 70-79 years) and 80s (n = 125, 80-89 years) were included. The PV was measured by transrectal ultrasonography, and the PSA level was determined using immunoradioassay. RESULTS No significant differences were found in the serum PSA levels between the men in their 70s and 80s (P = .128). However, the 95th percentile of the serum PSA level was 5.23 and 6.60 ng/mL in those in their 70s and 80s, respectively. The men in their 80s had a greater total PV and transitional volume than did men in their 70s (P = .026 and P = .009, respectively). The PV and PSA level correlated with age (P = .034), and the increase in PV stratified by PSA was statistically significant (P < .0001). CONCLUSIONS Although the PV had increased steadily in octogenarian men, the serum PSA level of men in their 80s did not show a significant difference compared with men in their 70s. We suggest that PSA is a good surrogate marker for PV, even in octogenarian men. | ko_KR |
dc.description.sponsorship | This work was supported by an Independent Research Grant from Pfizer Global
Pharmaceuticals (grant 06-05-039) and by the Developing Seongnam Health Promotion Program for the Elderly from the Seongnam City Government in the Republic of Korea (grant 800-20050211). | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | ELSEVIER SCIENCE INC | ko_KR |
dc.title | Changes in Prostate-specific Antigen Levels and Prostate Volume in Octogenarian Men: Community-based Study | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 정재승 | - |
dc.contributor.AlternativeAuthor | 변석수 | - |
dc.contributor.AlternativeAuthor | 한병규 | - |
dc.contributor.AlternativeAuthor | 정성진 | - |
dc.contributor.AlternativeAuthor | 홍성규 | - |
dc.contributor.AlternativeAuthor | 이상은 | - |
dc.identifier.doi | 10.1016/j.urology.2008.07.060 | - |
dc.citation.journaltitle | UROLOGY | - |
dc.description.citedreference | Lee SE, 2008, UROLOGY, V71, P395, DOI 10.1016/j.urology.2007.10.019 | - |
dc.description.citedreference | Kim KI, 2008, HYPERTENS RES, V31, P97 | - |
dc.description.citedreference | Choi YD, 2007, UROLOGY, V70, P1113, DOI 10.1016/j.urology.2007.07.063 | - |
dc.description.citedreference | Bosch JLHR, 2007, PROSTATE, V67, P1816, DOI 10.1002/pros.20663 | - |
dc.description.citedreference | Bohnen AM, 2007, EUR UROL, V51, P1645, DOI 10.1016/j.eururo.2007.01.084 | - |
dc.description.citedreference | Park SK, 2006, PROSTATE, V66, P1285, DOI 10.1002/pros.20419 | - |
dc.description.citedreference | Chang YL, 2006, J UROLOGY, V176, P196, DOI 10.1016/S0022-5347(06)00568-4 | - |
dc.description.citedreference | Chung BH, 2006, BJU INT, V97, P742, DOI 10.1111/j.1464-410X.2006.06016.x | - |
dc.description.citedreference | Bosch JLHR, 2004, EUR UROL, V46, P753, DOI 10.1016/j.eururo.2004.07.019 | - |
dc.description.citedreference | Mochtar CA, 2003, EUR UROL, V44, P695, DOI 10.1016/S0302-2838(03)00384-1 | - |
dc.description.citedreference | Roehrborn CG, 1999, UROLOGY, V53, P581 | - |
dc.description.citedreference | Ziada A, 1999, UROLOGY, V53, P1 | - |
dc.description.citedreference | DeAntoni EP, 1996, UROLOGY, V48, P234 | - |
dc.description.citedreference | Masumori N, 1996, J UROLOGY, V155, P1324 | - |
dc.description.citedreference | OESTERLING JE, 1995, BRIT J UROL, V75, P347 | - |
dc.description.citedreference | DALKIN BL, 1993, J UROLOGY, V150, P1837 | - |
dc.description.citedreference | OESTERLING JE, 1993, JAMA-J AM MED ASSOC, V270, P860 | - |
dc.description.citedreference | COLLINS GN, 1993, BRIT J UROL, V71, P445 | - |
dc.description.citedreference | *KOR NAT STAT OFF, PERC DISTR 65 YEARS | - |
dc.description.tc | 0 | - |
- Appears in Collections:
- Files in This Item:
- There are no files associated with this item.
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.