Publications
Detailed Information
Resistance Exercise Did Not Alter Intramuscular Adipose Tissue but Reduced Retinol-binding Protein-4 Concentration in Individuals with Type 2 Diabetes Mellitus
Cited 0 time in
Web of Science
Cited 0 time in Scopus
- Authors
- Issue Date
- 2010-06
- Publisher
- FIELD HOUSE PUBLISHING LLP
- Citation
- JOURNAL OF INTERNATIONAL MEDICAL RESEARCH; Vol.38 3; 782-791
- Keywords
- DIABETES MELLITUS TYPE 2 ; RETINOL-BINDING PROTEINS ; ADIPOSE TISSUE ; RESISTANCE TRAINING ; INSULIN RESISTANCE
- Abstract
- Lipid accumulation in muscle is associated with diminished insulin sensitivity. It was hypothesized that resistance exercise decreases muscular adipose tissue and reduces the level of retinol-binding protein-4 (RBP4), which is linked to adipose tissue and insulin sensitivity in diabetics. Forty-four women with type 2 diabetes were randomly assigned to three groups for a period of 12 weeks: control (asked to maintain a sedentary lifestyle); resistance exercise (elastic band exercise at moderate intensity five times per week); and aerobic exercise (walking for 60 min at moderate intensity five times per week). Subcutaneous (SCAT), subfascial (SFAT) and intramuscular (IMAT) adipose tissues at mid-thigh level were assessed using computed tomography, and RBP4 level and insulin sensitivity (fractional disappearance rate of insulin, km) were assessed before and after intervention. Changes in SCAT, SFAT, IMAT, RBP4 and km were similar among the three groups. Within-group analysis revealed that body mass index and waist circumference decreased significantly in both exercise groups, but RBP4 decreased significantly only with resistance exercise. Resistance exercise did not alter muscular adipose tissue or improve insulin sensitivity.
- ISSN
- 0300-0605
- Language
- English
- Appears in Collections:
Item View & Download Count
Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.