Browse

Changes in neuropsychological functioning following temporal lobectomy in patients with temporal lobe epilepsy

Cited 14 time in Web of Science Cited 17 time in Scopus
Authors
Shin, Min-Sup; Lee, SangKun; Seol, Soon-Ho; Lim, Young-Jin; Sergeant, Joseph A.; Chung, ChunKee; Park, Eun-Hee
Issue Date
2009-09
Publisher
MANEY PUBLISHING
Citation
NEUROLOGICAL RESEARCH; Vol.31 7; 692-701
Keywords
Executive functionmemorytemporal resectionTLEhippocampal sclerosis
Abstract
Purpose: This study was conducted to evaluate the changes in neuropsychological functioning in patients with temporal lobe epilepsy (TLE) after temporal lobe resection. Methods: Fifty-four TLE patients were evaluated before and after surgery using comprehensive neuropsychological tests to assess general intelligence, executive functioning, language, verbal and visual memory, working memory, visuo-spatial ability, attention and motor function. Results: The patients with left TLE showed no impairment of neuropsychological functioning after surgery, with the exception of auditory immediate memory. Furthermore, they showed significant improvement in performance IQ, executive function, working memory, visual memory, attention and psychomotor speed. The patients with right TLE did not show any significant impairment in post-operative neuropsychological functioning. They showed improvements in intellectual and executive functions, language, visual memory, visuo-spatial ability, attention and motor function post-operatively. The patients with hippocampal sclerosis showed greater post-operative improvements than the patients without hippocampal sclerosis regardless of the side. Patients with better pre-operative neuropsychological function had a higher chance of successfully discontinuing all seizure medications after surgery. Discussion: The results of this study suggest that temporal lobectomy does not harm the neuropsychological functioning of patients with intractable TLE and that it improves cognitive functions of the contralateral hemisphere. [Neurol Res 2009; 31: 692-701]
ISSN
0161-6412
Language
English
URI
http://hdl.handle.net/10371/77459
DOI
https://doi.org/10.1179/174313209X389848
Files in This Item:
There are no files associated with this item.
Appears in Collections:
College of Medicine/School of Medicine (의과대학/대학원)Dept. of Neurology (신경과학교실)Journal Papers (저널논문_신경과학교실)
  • mendeley

Items in S-Space are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse