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Association between colorectal adenoma and coronary atherosclerosis detected by CT coronary angiography in Korean men; a cross-sectional study
DC Field | Value | Language |
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dc.contributor.author | Yang, Sun Young | - |
dc.contributor.author | Kim, Young Sun | - |
dc.contributor.author | Chung, Su Jin | - |
dc.contributor.author | Song, Ji Hyun | - |
dc.contributor.author | Park, Min Jung | - |
dc.contributor.author | Lim, Seon Hee | - |
dc.contributor.author | Kim, Chung Hyun | - |
dc.contributor.author | Song, In Sung | - |
dc.contributor.author | Kim, Ju Sung | - |
dc.contributor.author | Kim, Donghee | - |
dc.contributor.author | Yim, Jeong Yoon | - |
dc.contributor.author | Choi, Su Yeon | - |
dc.date.accessioned | 2012-06-27T08:53:59Z | - |
dc.date.available | 2012-06-27T08:53:59Z | - |
dc.date.issued | 2010-11 | - |
dc.identifier.citation | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY; Vol.25 11; 1795-1799 | ko_KR |
dc.identifier.issn | 0815-9319 | - |
dc.identifier.uri | https://hdl.handle.net/10371/77660 | - |
dc.description.abstract | Background: Colorectal adenoma and coronary artery disease (CAD) appear to share common risk factors, such as male gender, diabetes mellitus, smoking, and obesity. We investigated the relationship between colorectal adenoma and coronary atherosclerosis, as a risk factor for colorectal adenoma. Methods: A cross-sectional study was conducted on Korean men who presented for a health check-up. The subjects were 488 men (217 colorectal adenoma and 271 normal colonoscopic findings) who underwent colonoscopy and coronary computed tomography angiography (CTA) on the same day as a screening examination. Advanced colonic lesion was defined as a presence of adenoma with villous component, high-grade dysplasia, and/or with size of >= 1 cm. CTA findings were classified as normal, mild (low-grade atherosclerosis or < 50% stenosis), and significant CAD (>= 50% stenosis). Abnormal CTA findings included mild and significant CAD. Results: Patients with abnormal CTA findings were more likely to have colorectal adenoma compared with those with normal CTA findings (P < 0.005). Furthermore, presence of advanced adenoma was significantly associated with significant CAD (P < 0.01). On multivariate analyses, abnormal CTA findings (OR = 1.66, 95% CI: 1.14-2.41, P < 0.01) and significant CAD (OR = 1.96, 95% CI: 1.15-3.35, P < 0.05) were found to be independent risk factors for colorectal adenoma after adjusting for age, current smoking, and metabolic syndrome. Conclusions: In this study, in the population who underwent CTA and colonoscopy for health check-up, prevalence of colorectal adenoma was greater in subjects with low-grade coronary atherosclerosis or significant CAD. The presence of advanced adenoma was significantly associated with significant CAD. | ko_KR |
dc.language.iso | en | ko_KR |
dc.publisher | WILEY-BLACKWELL | ko_KR |
dc.subject | colorectal adenoma | ko_KR |
dc.subject | coronary angiography | ko_KR |
dc.subject | computed tomography | ko_KR |
dc.subject | coronary atherosclerosis | ko_KR |
dc.subject | risk factor | ko_KR |
dc.subject | coronary artery disease | ko_KR |
dc.title | Association between colorectal adenoma and coronary atherosclerosis detected by CT coronary angiography in Korean men; a cross-sectional study | ko_KR |
dc.type | Article | ko_KR |
dc.contributor.AlternativeAuthor | 양선영 | - |
dc.contributor.AlternativeAuthor | 김영순 | - |
dc.contributor.AlternativeAuthor | 정수진 | - |
dc.contributor.AlternativeAuthor | 송지현 | - |
dc.contributor.AlternativeAuthor | 최수연 | - |
dc.contributor.AlternativeAuthor | 박민정 | - |
dc.contributor.AlternativeAuthor | 임정윤 | - |
dc.contributor.AlternativeAuthor | 임선희 | - |
dc.contributor.AlternativeAuthor | 김동희 | - |
dc.contributor.AlternativeAuthor | 김정현 | - |
dc.contributor.AlternativeAuthor | 김주성 | - |
dc.contributor.AlternativeAuthor | 송인성 | - |
dc.identifier.doi | 10.1111/j.1440-1746.2010.06330.x | - |
dc.citation.journaltitle | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | - |
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dc.description.tc | 1 | - |
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